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首页> 外文期刊>Journal of geriatric oncology >Authors' reply to Drs. Khattak and Martin. Intraperitoneal chemotherapy in older women with epithelial ovarian cancer.
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Authors' reply to Drs. Khattak and Martin. Intraperitoneal chemotherapy in older women with epithelial ovarian cancer.

机译：作者对博士的答复。哈塔克和马丁。老年妇女上皮性卵巢癌的腹腔内化疗。

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摘要

We would like to thank Drs. Khattak and Martin for their interest in our paper [1] and insightful comments. We agree that our study is limited by its retrospective nature and by the fact that it was conducted in a highly selected population referred to a tertiary care cancer center. Patients who received first-line intravenous/intraperitoneal chemotherapy in our study were treated with a modified GOG 172 regimen. Our group has recently published our experience using this modified outpatient regimen and has shown that it was associated with reduced toxicity and similar survival outcomes compared to GOG 172 [2,3]- In older patients, we would recommend the use of a modified GOG 172 regimen with appropriate supportive care measures, such as intravenous hydration, during treatment. Dr. Hurria is currently conducting a prospective trial in older patients to determine if toxicity can be predicted using an assessment tool for older patients with cancer (NCT00477958).
机译：我们要感谢博士。 Khattak和Martin对我们的论文[1]和有见地的评论感兴趣。我们同意，我们的研究受到其回顾性研究的局限性，并且受到在三级护理癌症中心指定的高度选定人群中进行的事实的限制。在我们的研究中接受一线静脉/腹膜内一线化疗的患者接受了改良的GOG 172方案治疗。我们小组最近发表了使用这种改良门诊治疗方案的经验，并显示与GOG 172相比，这种疗法与降低的毒性和相似的生存结果相关[2,3]-在老年患者中，我们建议使用改良的GOG 172治疗期间应采取适当的支持护理措施，例如静脉补水。 Hurria博士目前正在对老年患者进行前瞻性试验，以确定是否可以使用评估工具针对老年癌症患者（NCT00477958）预测毒性。

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