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首页> 外文期刊>Journal of geriatric psychiatry and neurology >Frontotemporal Dementia: An Updated Clinician's Guide
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Frontotemporal Dementia: An Updated Clinician's Guide

机译:额颞叶痴呆:最新临床医生指南

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Today, frontotemporal dementia (FTD) remains one of the most common forms of early-onset dementia, that is, before the age of 65, thus posing several diagnostic challenges to clinicians since symptoms are often mistaken for psychiatric or neurological diseases causing a delay in correct diagnosis, and the majority of patients with FTD present with symptoms at ages between 50 and 60. Genetic components are established risk factors for FTD, but the influence of lifestyle, comorbidity, and environmental factors on the risk of FTD is still unclear. Approximately 40% of individuals with FTD have a family history of dementia but less than 10% have a clear autosomal dominant pattern of inheritance. Lack of insight is often an early clue to FTD. A tailored treatment option at an early phase can mitigate suffering and improve patients' and caregivers' quality of life.
机译:如今,额颞叶痴呆(FTD)仍然是最常见的早发性痴呆形式之一,也就是说,在65岁之前,由于症状经常被误认为是精神病或神经病,导致延迟性痴呆,因此对临床医生提出了一些诊断挑战正确的诊断,大多数FTD患者在50至60岁之间出现症状。遗传因素是FTD的既定危险因素,但生活方式,合并症和环境因素对FTD风险的影响仍不清楚。约40%的FTD患者具有痴呆症家族史,但不到10%的患者具有明显的常染色体显性遗传。缺乏见识通常是FTD的早期线索。在早期阶段量身定制的治疗方案可以减轻痛苦并改善患者和护理人员的生活质量。

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