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首页> 外文期刊>Clinical Pediatrics >Functional endoscopic sinus surgery improves sinus-related symptoms and quality of life in children with chronic rhinosinusitis: A systematic analysis and meta-analysis of published interventional studies
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Functional endoscopic sinus surgery improves sinus-related symptoms and quality of life in children with chronic rhinosinusitis: A systematic analysis and meta-analysis of published interventional studies

机译：功能性内窥镜鼻窦手术可改善慢性鼻-鼻窦炎患儿的鼻窦相关症状和生活质量：已发表干预研究的系统分析和荟萃分析

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Aim. To assess the current knowledge and evaluate the quality of evidence in the use of FESS for the treatment of chronic rhinosinusitis in children, regarding the respective changes in the quality-of-their-life (QoL) and the outcome that follows the operation. Materials/Methods. Systematic literature review in Medline and other database sources and meta-analysis of pooled data. Results. 15 studies were systematically analyzed. Four represented Level II, five Level III, and six Level IV evidence. The total number of treated patients was 1301. Thirteen research groups reported that pediatric FESS is an effective treatment for chronic rhinosinusitis; the respective positive outcome ranged between 71 and 100% of operated children. Five studies concluded that this treatment modality is associated with significant improvement in the children's postoperative QoL. Systemic diseases and environmental factors may have unfavourable prognostic effects; cystic fibrosis is associated with at least 50% recurrence rate. The rate of major complications following pediatric FESS is 0.6%, and the respective rate of minor complications 2%. Conclusion. The surgical management in children with chronic rhinosinusitis, despite the reservations expressed by many clinicians, is effective when optimal medical treatment proves unsuccessful (grade B strength of recommendation), and is associated with improvement in the children's QoL (grade B strength of recommendation). FESS also improves the sinusitis-associated symptoms and QoL in children with cystic fibrosis (grade C strength of recommendation. Most complications of pediatric FESS reported in the literature are minor, and associated with difficulties in the postoperative assessment and care of pediatric patients.
机译：目标。为了评估当前的知识并评估使用FESS治疗儿童慢性鼻-鼻窦炎的证据质量，以及其生活质量（QoL）的相应变化以及手术后的结局。材料/方法。 Medline和其他数据库资源中的系统文献综述以及汇总数据的荟萃分析。结果。系统分析了15项研究。四个代表II级，五个代表III级，六个代表IV级证据。接受治疗的患者总数为1301。十三个研究小组报告说，小儿FESS是治疗慢性鼻-鼻窦炎的有效方法。各自的积极结果介于71％到100％的手术儿童之间。五项研究得出结论，这种治疗方式与儿童术后生活质量的显着改善有关。系统性疾病和环境因素可能会对预后产生不利影响;囊性纤维化的复发率至少为50％。小儿FESS术后主要并发症的发生率为0.6％，次要并发症的发生率为2％。结论。尽管许多临床医生表示保留意见，但慢性鼻鼻窦炎儿童的外科手术治疗在最佳药物治疗不成功（推荐B级强度）时有效，并与儿童QoL改善（推荐B级强度）相关。 FESS还改善了囊性纤维化患儿的鼻窦炎相关症状和QoL（推荐C级强度。文献中报道的小儿FESS并发症多数较小，并且与小儿患者的术后评估和护理困难有关）。

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