A p38 MAPK Inhibitor Improves Outcome After Glaucoma Filtration Surgery

Nassar Khaled; Tura Aysegul; Lueke Julia; Lueke Matthias; Grisanti Salvatore; Grisanti Swaantje

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A p38 MAPK Inhibitor Improves Outcome After Glaucoma Filtration Surgery

机译：p38 MAPK抑制剂可改善青光眼滤过术后的结果

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摘要

Purpose: The aim of this study is to explore the effects of SB 202190, a highly selective p38 MAPK inhibitor, on bleb survival following glaucoma filtering surgery.

机译：目的：本研究的目的是探讨高度选择性的p38 MAPK抑制剂SB 202190对青光眼滤过术后小泡存活的影响。

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来源
《Journal of glaucoma》 |2015年第2期|共14页
作者
Nassar Khaled; Tura Aysegul; Lueke Julia; Lueke Matthias; Grisanti Salvatore; Grisanti Swaantje;
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原文格式 PDF
正文语种 eng
中图分类眼科学;
关键词
glaucoma; filtration surgery; wound healing; p38 mitogen-activated protein kinases; SB 202190;

机译：青光眼;过滤手术;伤口愈合;p38丝裂原活化蛋白激酶;SB 202190;

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专利

1. A p38 MAPK Inhibitor Improves Outcome After Glaucoma Filtration Surgery [J] . Nassar Khaled, Tura Aysegul, Lueke Julia, Journal of glaucoma . 2015,第2期

机译：p38 MAPK抑制剂可改善青光眼滤过术后的结果
2. Novel ASK1 inhibitor AGI‐1067 improves AGE‐induced cardiac dysfunction by inhibiting MKKs/p38 MAPK and NF‐κB apoptotic signaling [J] . Zhongwei Liu, Shixiang Zheng, Xi Wang, FEBS Open Bio . 2018,第9期

机译：新型ASK1抑制剂AGI-1067通过抑制MKKs / p38 MAPK和NF-κB凋亡信号转导改善AGE引起的心脏功能障碍
3. Novel ASK1 inhibitor AGI‐1067 improves AGE‐induced cardiac dysfunction by inhibiting MKKs/p38 MAPK and NF‐κB apoptotic signaling [J] . Zhongwei Liu, Shixiang Zheng, Xi Wang, FEBS Open Bio . 2018,第9期

机译：新型ASK1抑制剂AGI-1067通过抑制MKKs / p38 MAPK和NF-κB凋亡信号转导改善AGE引起的心脏功能障碍
4. Targeted Delivery of p38 MAPK Inhibitors for Multiple Sclerosis Therapy [C] . Rachael A. Oldinski, Tianxin Miao, Abbas Raza, Society for Biomaterials annual meeting and exposition . 2017

机译：p38 MAPK抑制剂靶向递送的多发性硬化症治疗
5. Novel methods for the modulation of wound healing after glaucoma filtration surgery [D] . Georgoulas, Stylianos D. 2010

机译：青光眼过滤手术后伤口愈合调节的新方法
6. CDDO-Me Inhibits Microglial Activation and Monocyte Infiltration by Abrogating NFκB- and p38 MAPK-Mediated Signaling Pathways Following Status Epilepticus [O] . Ji-Eun Kim, Hana Park, Ji-Eun Lee, 2020

机译：CDDO-Me通过抑制癫痫持续状态后废除NFκB和p38 MAPK介导的信号通路来抑制小胶质细胞活化和单核细胞浸润
7. Sustained compensatory p38 MAPK signaling following treatment with MAPK inhibitors induces the immunosuppressive protein CD73 in cancer: combined targeting could improve outcomes [O] . Mikkel G. Terp, Odd L. Gammelgaard, Henriette Vever, 2021

机译：用MAPK抑制剂治疗后持续补偿P38 MAPK信号传导诱导癌症中的免疫抑制蛋白CD73：组合靶向可以改善结果

A p38 MAPK Inhibitor Improves Outcome After Glaucoma Filtration Surgery

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