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首页> 外文期刊>Clinical Pediatrics >Are nasopharyngeal cultures useful in diagnosis of acute bacterial sinusitis in children?
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Are nasopharyngeal cultures useful in diagnosis of acute bacterial sinusitis in children?

机译：鼻咽培养物对儿童急性细菌性鼻窦炎的诊断有用吗？

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摘要

The diagnosis of acute bacterial sinusitis can be challenging because symptoms of acute sinusitis and an upper respiratory tract infection (URI) overlap. A rapid test, if accurate in differentiating sinusitis from URI, could be helpful in the diagnostic process. We examined the utility of nasopharyngeal cultures in identifying the subgroup of children with a clinical diagnosis of acute sinusitis who are least likely to benefit from antimicrobial therapy (those with completely normal sinus radiographs). Nasopharyngeal swabs were collected from 204 children meeting a priori clinical criteria for acute sinusitis. All children had sinus X-rays at the time of diagnosis. To determine if negative nasopharyngeal culture results could reliably identify the subgroup of children with normal radiographs, we calculated negative predictive values and negative likelihood ratios. Absence of pathogens in the nasopharynx was not helpful in identifying this low-risk subgroup.
机译：急性细菌性鼻窦炎的诊断可能具有挑战性，因为急性鼻窦炎和上呼吸道感染（URI）的症状重叠。如果准确地将鼻窦炎与URI鉴别，快速检查可能对诊断过程很有帮助。我们检查了鼻咽文化在确定临床诊断为急性鼻窦炎的儿童亚组中的效用，这些儿童最不可能从抗菌治疗中受益（那些鼻窦射线照相完全正常的儿童）。从满足急性鼻窦炎先验临床标准的204名儿童中收集鼻咽拭子。所有儿童在诊断时均接受过鼻窦X光检查。为了确定阴性的鼻咽培养结果是否可以可靠地确定X光片正常的儿童亚组，我们计算了阴性预测值和阴性似然比。鼻咽中缺乏病原体无助于确定这一低风险亚组。

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