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首页> 外文期刊>Journal of health communication >Testing different communication formats on responses to imagined risk of having versus missing the GSTM1 gene
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Testing different communication formats on responses to imagined risk of having versus missing the GSTM1 gene

机译：测试不同的通讯格式，以应对预期的具有或缺失GSTM1基因的风险

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摘要

Genetic markers of lung cancer susceptibility, such as the common variant of the glutathione S-transferase Mu 1 gene (GSTM1-null), confer small probabilities of disease risk. The authors explored the influence of different approaches to communicating the small variations in risk associated with this biomarker. College smokers (N = 128) imagined that they had the GSTM1 wild-type variant versus the GSTM1 null-type variant. The authors presented lung cancer risk in 6 ways that varied the risk format (absolute risk vs. incremental risk) and the presentation style of the information (no graphics vs. graphic display of foreground only vs. graphic display of foreground + background). Presentation style had minor effects. However, absolute risk information increased negative emotions more than did incremental risk information. Perceptions of risk and negative emotions were most profoundly affected by the difference between having the GSTM1 wild-type variant versus the GSTM1 null-type variant. The authors discuss implications for conveying small probabilities related to genetic risk.
机译：肺癌易感性的遗传标志物，例如谷胱甘肽S-转移酶Mu 1基因的常见变体（GSTM1-null），具有较小的患病风险的概率。作者探讨了不同方法传播与该生物标志物相关的风险的小变化的影响。高校吸烟者（N = 128）认为他们拥有GSTM1野生型变异体与GSTM1空类型变异体。作者通过6种方式介绍了肺癌风险，这些方式改变了风险的格式（绝对风险与增量风险）和信息的呈现方式（无图形与仅前景的图形显示与前景+背景的图形显示）。演示样式影响较小。但是，绝对风险信息比增加风险信息增加了更多的负面情绪。风险和负面情绪的感知受GSTM1野生型变异体与GSTM1空类型变异体之间的差异影响最大。作者讨论了传达与遗传风险有关的小概率的含义。

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