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首页> 外文期刊>Journal of gastroenterology and hepatology >Proposal of a new diagnostic algorithm for hepatocellular carcinoma based on the Japanese guidelines but adapted to the Western world for patients under surveillance for chronic liver disease
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Proposal of a new diagnostic algorithm for hepatocellular carcinoma based on the Japanese guidelines but adapted to the Western world for patients under surveillance for chronic liver disease

机译：根据日本指南制定一种新的肝细胞癌诊断算法的建议，但该方法适用于西方国家，适用于受慢性肝病监视的患者

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To date, despite many scientific evidences, the guidelines of the principal hepatological societies, such as the American Association for the Study of Liver Diseases, the European Association for the Study of the Liver, and the Asian Pacific Association for the Study of the Liver, do not recognize the diagnostic superiority of magnetic resonance imaging (MRI) over computed tomography in the diagnosis of hepatocellular carcinoma (HCC) and, for the most part, do not contemplate the use of hepatospecific contrast media, such as gadoliniumethoxybenzyl- diethylenetriamine pentaacetic acid (EOB). The aim of this paper was to analyze the recent results of EOB-MRI in the study of chronic liver disease and the differences between the American Association for the Study of Liver Diseases and the Japan Society of Hepatology guidelines, of which the latter represents the most consolidated experience on EOB-MRI use for HCC diagnosis. Finally, a new diagnostic algorithm for HCC in patients under surveillance for chronic liver disease was formulated, which contemplates the use of EOB. This new diagnostic algorithm is based on the Japan Society of Hepatology algorithm but goes beyond it by adapting it to the Western world, taking into account both the difference between the two and the latest results concerning the diagnosis of HCC. This new diagnostic algorithm for HCC is proposed in order to provide useful diagnostic tools to all those Western countries where the use of EOB (more expensive than extracellular contrast media) is widespread but in which common strategies to manage the nodules that this new contrast agent allows identifying have not been available to date.
机译：迄今为止，尽管有许多科学证据，但主要的肝病学会指南，例如美国肝病研究协会，欧洲肝病研究协会和亚洲太平洋肝病研究协会，在肝细胞癌（HCC）的诊断中没有认识到磁共振成像（MRI）在计算机断层扫描上的诊断优势，并且在大多数情况下，没有考虑使用肝特异性造影剂，例如g多酰iu甲氧基苄基二乙三胺五乙酸（ EOB）。本文的目的是分析EOB-MRI在研究慢性肝病方面的最新成果以及美国肝病研究协会和日本肝病学会指南之间的差异，其中后者代表了最多的差异EOB-MRI用于HCC诊断的综合经验。最后，制定了一种新的诊断慢性肝病患者肝癌的诊断算法，该算法考虑了EOB的使用。这种新的诊断算法基于日本肝病学会算法，但在考虑到两者之间的差异以及有关HCC诊断的最新结果的基础上，使其适应西方世界，从而超越了它。提出了这种针对HCC的新诊断算法，以便为所有广泛使用EOB（比细胞外造影剂价格昂贵）但使用这种新型造影剂可以控制结节的通用策略的西方国家提供有用的诊断工具迄今为止尚未提供识别信息。

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