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首页> 外文期刊>Journal of health communication >Take-wait-stop: A patient-centered strategy for writing PRN medication instructions
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Take-wait-stop: A patient-centered strategy for writing PRN medication instructions

机译：等待停止：以患者为中心的策略编写PRN药物说明

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摘要

Recent studies have linked patient misunderstanding of label instructions for as needed (PRN) medications to dosing errors. This study conducted a preliminary field test of patient-centered PRN label instructions. Patients participated in a hypothetical dosing experiment and were randomized to a patient-centered label (referred to as "Take-Wait-Stop") or standard label. Participants were asked to demonstrate dosing the medicine over 24 hours. Three types of independent dosing errors were measured: (a) taking more than two pills at one time, (b) exceeding the maximum daily dose, and (c) waiting fewer than 4 hours between doses. Generalized linear models were used to assess the association between label type, health literacy, and sociodemographic characteristics. Participants' mean age was 39.8 years, 62.1% were female, 43.7% were White, and 72.4% had adequate literacy. Of participants, 31.8% who were shown the standard label demonstrated taking in excess of 6 pills in 24 hours compared with only 14.0% of participants who were shown the Take-Wait-Stop label (p =.05). Overall, only 1 person demonstrated he would take more than 2 pills in a single dose. Of the standard label group, 20.5% demonstrated dosing intervals of fewer than 4 hours compared with 23.3% of the Take-Wait-Stop label group (p=.75). In a multivariate model, participants who were exposed to the standard label were 2.5 times more likely to exceed the recommended maximum daily dose (95% CI [1.05, 7.70], p=.03). The Take-Wait-Stop label was beneficial in preventing participants from exceeding the maximum dose in 24 hours, although it did not significantly reduce other dosing errors.
机译：最近的研究已将患者对按需（PRN）药物标签说明的误解与剂量错误联系在一起。这项研究对以患者为中心的PRN标签说明进行了初步的现场测试。患者参加了假设的剂量试验，并被随机分配到以患者为中心的标签（称为“停药-停药”）或标准标签。要求参与者证明24小时内服药。测量了三种类型的独立剂量错误：（a）一次服用超过两粒药;（b）超过最大每日剂量;（c）两次服药之间等待少于4小时。使用广义线性模型评估标签类型，健康素养和社会人口统计学特征之间的关联。参加者的平均年龄为39.8岁，女性为62.1％，白人为43.7％，识字率为72.4％。在接受标准标签的参与者中，有31.8％的参与者在24小时内服用了超过6片药，而在接受“停药-停止”标签的参与者中，只有14.0％（p = .05）。总体而言，只有1个人证明他一次服用2片以上的药。在标准标签组中，有20.5％的用药间隔少于4小时，而“停药-停止”标签组的用药间隔为23.3％（p = .75）。在多变量模型中，暴露于标准标签的参与者超过建议最大每日剂量的可能性是2.5倍（95％CI [1.05，7.70]，p = .03）。服药停停标签可以防止参与者在24小时内超过最大剂量，尽管它并不能显着减少其他给药错误。

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