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Discussions of cancer clinical trials with the national cancer institute's cancer information service

机译:与美国国家癌症研究所的癌症信息服务机构讨论癌症临床试验

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Clinical trials are essential for the development of new and effective treatments for cancer; however, participation rates are low. One reason for this is lack of knowledge about clinical trials. This study assessed how often clinical trials are discussed on calls to National Cancer Institute's Cancer Information Service (CIS). The authors quantitatively analyzed 283,094 calls to the CIS (1-800-4-CANCER) over 3 years (2006-2008). They calculated descriptive statistics and multivariate regressions to determine whether specific caller characteristics are associated with the presence of a clinical trials discussion. In addition, 2 focus groups were conducted with CIS information specialists (n=12) to provide insight into the findings. The authors found that approximately 9.3% of CIS calls discussed clinical trials, with higher percentages for patients (12.5%) and family members (15.4%). Calls with Hispanics, Blacks, and Spanish speakers were less likely to include a conversation. For all cancers, patients who are in treatment or experiencing a recurrence were statistically significantly more likely to discuss clinical trials. CIS information specialists reported callers limited knowledge of clinical trials. The CIS has the unique ability to make a substantial effect in educating patients about clinical trials as an option in cancer treatment and care.
机译:临床试验对于开发新的有效癌症治疗方法至关重要。但是,参与率很低。原因之一是缺乏对临床试验的了解。这项研究评估了致电美国国家癌症研究所的癌症信息服务(CIS)讨论临床试验的频率。作者定量分析了过去3年(2006-2008年)向CIS(1-800-4-CANCER)进行的283,094个呼叫。他们计算了描述性统计数据和多元回归,以确定特定的呼叫者特征是否与临床试验讨论相关。此外,还与CIS信息专家(n = 12)进行了2个焦点小组的交流,以深入了解研究结果。作者发现,大约9.3%的CIS呼叫讨论了临床试验,其中患者(12.5%)和家庭成员(15.4%)的百分比更高。与西班牙裔,黑人和西班牙裔讲者打来的电话不太可能包含对话。对于所有癌症,正在治疗或复发的患者在统计学上更有可能讨论临床试验。 CIS信息专家报告称,呼叫者对临床试验的了解有限。 CIS具有独特的能力,可以在教育患者有关临床试验方面发挥实质性作用,作为癌症治疗和护理的一种选择。

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