SAFETY, TOLERABILITY AND PHARMACOKINETIC OF GIC-1001 FOLLOWING MULTIPLE ASCENDING DOSES ADMINISTRATIONS THROUGH AN ADAPTIVE FIRST IN HUMAN STUDY IN HEALTHY VOLUNTEERS.

Paquette J. M.; Rufiange M.; Sadoune A. Ait; Sicard E.; Massicotte J.; Lefebvre M.; Colin P.; Ranger M.

首页> 外文期刊>Clinical Pharmacology and Therapeutics >SAFETY, TOLERABILITY AND PHARMACOKINETIC OF GIC-1001 FOLLOWING MULTIPLE ASCENDING DOSES ADMINISTRATIONS THROUGH AN ADAPTIVE FIRST IN HUMAN STUDY IN HEALTHY VOLUNTEERS.

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SAFETY, TOLERABILITY AND PHARMACOKINETIC OF GIC-1001 FOLLOWING MULTIPLE ASCENDING DOSES ADMINISTRATIONS THROUGH AN ADAPTIVE FIRST IN HUMAN STUDY IN HEALTHY VOLUNTEERS.

机译：GIC-1001的安全性，耐受性和药代动力学是在健康志愿者的人体研究中首先通过自适应剂量多次给药的。

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《Clinical Pharmacology and Therapeutics》 |2014年第1期|共1页
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Paquette J. M.; Rufiange M.; Sadoune A. Ait; Sicard E.; Massicotte J.; Lefebvre M.; Colin P.; Ranger M.;
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正文语种 eng
中图分类药理学;
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1. SAFETY, TOLERABILITY AND PHARMACOKINETIC OF GIC-1001 FOLLOWING MULTIPLE ASCENDING DOSES ADMINISTRATIONS THROUGH AN ADAPTIVE FIRST IN HUMAN STUDY IN HEALTHY VOLUNTEERS. [J] . Paquette J. M., Rufiange M., Sadoune A. Ait, Clinical Pharmacology and Therapeutics . 2014,第Suppla1期

机译：GIC-1001的安全性，耐受性和药代动力学是在健康志愿者的人体研究中首先通过自适应剂量多次给药的。
2. Safety, Tolerability and Pharmacokinetics of Trimebutine 3-Thiocarbamoylbenzenesulfonate (GIC-1001) in a Randomized Phase I Integrated Design Study: Single and Multiple Ascending Doses and Effect of Food in Healthy Volunteers [J] . Paquette Jean-Michel, Rufiange Marianne, Niculita Mirela Iovu, Clinical therapeutics . 2014,第11期

机译：曲美布汀3-硫代氨基甲酰基苯磺酸盐（GIC-1001）的随机I期集成设计研究的安全性，耐受性和药代动力学：健康志愿者中的单次和多次递增剂量及食物的作用
3. Pharmacokinetics, Safety, and Tolerability of R411, a Dual {alpha}4{beta}1-{alpha}4{beta}7 Integrin Antagonist After Oral Administration at Single and Multiple Once-Daily Ascending Doses in Healthy Volunteers. [J] . Hijazi Y, Dorr AE, Blain R, The Journal of Clinical Pharmacology: Official Journal of the American College of Clinical Pharmacology . 2004,第12期

机译：在健康志愿者中以单次和多次每日递增剂量口服后，双重的{α} 4 {beta} 1- {alpha} 4 {beta} 7整联蛋白拮抗剂R411的药代动力学，安全性和耐受性。
4. Pharmacokinetics and Tolerability of Sublingual Fentanyl in Healthy Japanese and Caucasian Volunteers: Phase I, Open-Label Single-Dose Study [C] . U. Lorch, F. Farrell, J. Kilborn, International Pain Clinic Congress . 2008

机译：健康日本和白种人志愿者舌下芬太尼的药代动力学和耐受性：I期，开放标签单剂量研究
5. Pharmacokinetics, tissue depletion, target animal safety and live animal swab test accuracy after administration of long-acting oxytetracycline at double the label dose in healthy calves. [D] . TerHune, Terry Norman. 1988

机译：在健康小牛中，以双倍剂量服用长效土霉素后，药代动力学，组织耗竭，目标动物安全性和活体拭子测试准确性。
6. A Five-in-One First-in-Human Study To Assess Safety Tolerability and Pharmacokinetics of RO7049389 an Inhibitor of Hepatitis B Virus Capsid Assembly after Single and Multiple Ascending Doses in Healthy Participants [O] . Sheng Feng, Edward Gane, Christian Schwabe, 2020

机译：一项五联的一体化研究以评估RO7049389的安全性耐受性和药代动力学乙型肝炎病毒衣壳组装的抑制剂在健康参与者中单一和多个升序剂量之后
7. A Five-in-One First-in-Human Study To Assess Safety, Tolerability, and Pharmacokinetics of RO7049389, an Inhibitor of Hepatitis B Virus Capsid Assembly, after Single and Multiple Ascending Doses in Healthy Participants [O] . Sheng Feng, Edward Gane, Christian Schwabe, 2020

机译：一项五联的一体化研究，以评估RO7049389的安全性，耐受性和药代动力学，乙型肝炎病毒衣壳组装的抑制剂，在健康参与者中单一和多个升序剂量之后

SAFETY, TOLERABILITY AND PHARMACOKINETIC OF GIC-1001 FOLLOWING MULTIPLE ASCENDING DOSES ADMINISTRATIONS THROUGH AN ADAPTIVE FIRST IN HUMAN STUDY IN HEALTHY VOLUNTEERS.

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