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首页> 外文期刊>Journal of hepato-biliary-pancreatic surgery >Assessment of hepatic reserve for indication of hepatic resection: how I do it.
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Assessment of hepatic reserve for indication of hepatic resection: how I do it.

机译：评估肝储备以指示肝切除的方法：我该怎么做。

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BACKGROUND/PURPOSE: Hepatic resection may result in liver failure in patients with cirrhotic livers. Preoperative evaluation of liver function in cirrhotic patients, to prevent postoperative liver failure, is very important. METHODS: Sixteen patients with hepatocellular carcinoma in cirrhotic livers were enrolled in this study. Liver function was determined quantitatively by monoethylglycinexylidide (MEGX) formation from the metabolism of lidocaine. The whole liver volume and tumor volume were measured by computed tomographic volumetry. The volume of resected liver was recorded by water displacement. The relationship between liver function and remnant liver volume was determined. RESULTS: A relationship between the percentage remnant liver volume and ratio of MEGX formation after hepatectomy was found. The regression equation was: (postoperative MEGX formation/preoperative MEGX formation) x 100% = (0.688 x percentage remnant liver volume + 0.179) x 100% (r (2) = 0.49). A relationship between MEGX formation after hepatectomy and the international ratio (INR) of prothrombin time was also found. The regression equation was INR = 1.99 - 0.01 x MEGX (r (2) = 0.30). CONCLUSIONS: Post-hepatectomy liver function can be estimated for an individual patient by the appropriate regression equations. Prevention of post-hepatectomy liver failure for patients with cirrhotic livers is feasible.
机译：背景/目的：肝硬化患者肝切除可能会导致肝功能衰竭。肝硬化患者的术前评估肝功能，以防止术后肝功能衰竭，非常重要。方法：本研究纳入了16例肝硬化肝细胞性肝癌患者。肝功能由利多卡因代谢中的单乙基甘氨酰缩水甘油（MEGX）形成来定量测定。通过计算机断层摄影容量法测量全肝体积和肿瘤体积。通过排水记录切除的肝脏的体积。确定了肝功能与残余肝体积之间的关系。结果：发现肝切除术后残余肝体积百分比与MEGX形成比例之间存在关系。回归方程为：（术后MEGX形成/术前MEGX形成）×100％=（0.688 x残余肝脏体积百分比+ 0.179）×100％（r（2）= 0.49）。还发现了肝切除术后MEGX的形成与凝血酶原时间的国际比率（INR）之间的关系。回归方程为INR = 1.99-0.01 x MEGX（r（2）= 0.30）。结论：肝切除术后的肝功能可以通过适当的回归方程来估计。对于肝硬化肝患者，预防肝切除术后肝衰竭是可行的。

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