首页> 外文期刊>Journal of hepato-biliary-pancreatic surgery >Risk factors of posthepatectomy liver failure after portal vein embolization.
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Risk factors of posthepatectomy liver failure after portal vein embolization.

机译:肝切除术后门静脉栓塞后肝功能衰竭的危险因素。

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Background/Purpose. Major hepatectomy has been successfully performed after portal vein embolization (PE). However, posthepatectomy liver failure following hyperbilirubinemia (HB) sometimes occurs even after PE. Our objective was to determine what factors affected post-hepatectomy HB and liver failure. Methods. Forty-two patients underwent PE before major hepatectomy or repeat hepatic resection after partial hepatectomy. Having a prognostic score over 40, they all belonged to a high-risk group. They were classified into two groups according to posthepatectomy levels of total bilirubin: normal group and HB group. The HB group was further divided into two subgroups: recovered subgroup and fatal subgroup. We investigated the differences between the two groups and the two subgroups. Results. Ten of 14 cases (71%) in the HB group were biliary tract disease with jaundice before PE. The indocyanine green retention rate (ICGR15) before PE, skeletonization of the hepatoduodenal ligament (HDL), and portal venouspressure after PE were significantly different between the two groups as shown by multivariate analysis. Postoperative complication was the only factor significantly different between the two subgroups by univariate analysis. Conclusions. When the patients underwent major hepatectomy combined with skeletonization of the HDL for biliary tract disease with jaundice, they were subject to posthepatectomy HB even after PE. If they had postoperative complications, fatal hepatic failure must have occurred.
机译:背景/目的。门静脉栓塞(PE)后已成功进行了大肝切除术。但是,即使在PE后,高胆红素血症(HB)后肝切除术后的肝衰竭有时也会发生。我们的目标是确定哪些因素会影响肝切除术后的HB和肝功能衰竭。方法。 42例患者在大肝切除术前行PE或在部分肝切除术后再次行肝切除术。他们的预后评分均超过40,属于高危人群。根据肝切除术后总胆红素水平将其分为两组:正常组和HB组。 HB组又分为两个亚组:恢复亚组和致命亚组。我们调查了两组和两个亚组之间的差异。结果。 HB组14例中有10例(71%)为PE前黄疸性胆道疾病。多元分析显示,两组间PE前的吲哚菁绿保留率(ICGR15),肝十二指韧带(HDL)的骨架化以及PE后的门静脉压显着不同。通过单因素分析,术后并发症是两个亚组之间显着不同的唯一因素。结论。当患者接受大肝切除术并伴有HDL骨架化黄疸性胆道疾病时,即使在PE后也要进行肝切除术后HB。如果他们有术后并发症,则必须发生致命的肝衰竭。

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