Synthesis of some novel pyrazolo[1,5-a]pyrimidine, 1,2,4-triazolo[1,5-a]pyrimidine, pyrido[2,3-d]pyrimidine, pyrazolo[5,1-c]-1,2,4-triazine and 1,2,4-triazolo[5,1-c]-1,2,4-triazine derivatives incorporating a thiazolo[3,2-a]benzimidazole moiety

Abdel-Aziz HA; Hamdy NA; Farag AM; Fakhr IMI

首页> 外文期刊>Journal of Heterocyclic Chemistry: The International Journal of Heterocyclic Chemistry >Synthesis of some novel pyrazolo[1,5-a]pyrimidine, 1,2,4-triazolo[1,5-a]pyrimidine, pyrido[2,3-d]pyrimidine, pyrazolo[5,1-c]-1,2,4-triazine and 1,2,4-triazolo[5,1-c]-1,2,4-triazine derivatives incorporating a thiazolo[3,2-a]benzimidazole moiety

【24h】

Synthesis of some novel pyrazolo[1,5-a]pyrimidine, 1,2,4-triazolo[1,5-a]pyrimidine, pyrido[2,3-d]pyrimidine, pyrazolo[5,1-c]-1,2,4-triazine and 1,2,4-triazolo[5,1-c]-1,2,4-triazine derivatives incorporating a thiazolo[3,2-a]benzimidazole moiety

机译：一些新型吡唑并[1,5-a]嘧啶，1,2,4-三唑并[1,5-a]嘧啶，吡啶并[2,3-d]嘧啶，吡唑并[5,1-c] -1的合成并有噻唑并[3,2-a]苯并咪唑部分的1,2,4-三嗪和1,2,4-三唑并[5,1-c] -1,2,4-三嗪衍生物

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

E-3-(N,N-Dimethylamino)-1-(3-methylthiazolo[3,2-a]benzimidazol-2-yl)prop-2-en-1-one (2) was synthesized by the reaction of 1-(3-methylthiazolo[3,2-a]benzimidazol-2-yl)ethanone (1) with dimethylformamide-dimethylacetal. The reaction of 2 with 5-amino-3-phenyl-1H-pyrazole (4a) or 3-amino-1,2,4-(1H)-triazole (4b) furnished pyrazolo[1,5-a]pyrimidine and 1,2,4-triazolo[1,5-a]pyrimidine derivatives 6a and 6b, while the reaction of enaminone 2 with 6-aminopyrimidine derivatives 7a,b afforded pyrido[2,3-d]pyrimidine derivatives 9a,b, respectively. The diazonium salts 11a or 11b coupled with compound 2 to yield the pyrazolo[5,1-c]-1,2,4-triazine and 1,2,4-triazolo[5,1-c]-1,2,4-triazine derivatives 13a and 13b. Some of the newly synthesized compounds exhibited a moderate effect against some bacterial and fungal species.

机译：E-3-（N，N-二甲基氨基）-1-（3-甲基噻唑并[3,2-a]苯并咪唑-2-基）丙-2-烯-1-酮（2）通过1的反应合成-（3-甲基噻唑并[3，2-a]苯并咪唑-2-基）乙酮（1）与二甲基甲酰胺-二甲基乙缩醛。 2与5-氨基-3-苯基-1H-吡唑（4a）或3-氨基-1,2,4-（1H）-三唑（4b）的反应提供吡唑并[1,5-a]嘧啶和1 ，2，4-三唑并[1，5-a]嘧啶衍生物6a和6b，而烯胺酮2与6-氨基嘧啶衍生物7a，b的反应分别得到吡啶并[2，3-d]嘧啶衍生物9a，b。重氮盐11a或11b与化合物2偶联生成吡唑并[5,1-c] -1,2,4-三嗪和1,2,4-三唑并[5,1-c] -1,2,4 -三嗪衍生物13a和13b。一些新合成的化合物对某些细菌和真菌物种表现出中等作用。

著录项

来源
《Journal of Heterocyclic Chemistry: The International Journal of Heterocyclic Chemistry》 |2008年第4期|共5页
作者
Abdel-Aziz HA; Hamdy NA; Farag AM; Fakhr IMI;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类有机化学;
关键词
1; 3; 4-THIADIAZOLE; PYRAZOLE; PENDANT; ROUTE;

机译：1;3;4-噻唑;吡唑;链坠;路线;

相似文献

外文文献
中文文献
专利

1. Synthesis of some novel pyrazolo[1,5-a]pyrimidine, 1,2,4-triazolo[1,5-a]pyrimidine, pyrido[2,3-d]pyrimidine, pyrazolo[5,1-c]-1,2,4-triazine and 1,2,4-triazolo[5,1-c]-1,2,4-triazine derivatives incorporating a thiazolo[3,2-a]benzimidazole moiety [J] . Abdel-Aziz HA, Hamdy NA, Farag AM, Journal of Heterocyclic Chemistry: The International Journal of Heterocyclic Chemistry . 2008,第4期

机译：一些新型吡唑并[1,5-a]嘧啶，1,2,4-三唑并[1,5-a]嘧啶，吡啶并[2,3-d]嘧啶，吡唑并[5,1-c] -1的合成并有噻唑并[3,2-a]苯并咪唑部分的1,2,4-三嗪和1,2,4-三唑并[5,1-c] -1,2,4-三嗪衍生物
2. AN EFFICIENT SINGLE STEP SYNTHESIS OF PYRIDAZINE, PYRAZOLO[5,1-c]-1,2,4-TRIAZINE,1,2,4-TRIAZOLO[5,1-c]-1,2,4- TRIAZINE AND 1,2,4-TRIAZINO[4,3-a]BENZIMIDAZOLE DERIVATIVES [J] . Mohamed R. Shaaban, Tamer S. Saleh, Ahmad M. Farag Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry . 2009,第3期

机译：吡嗪，吡唑并[5,1-c] -1,2,4-三嗪，1,2,4-三唑并[5,1-c] -1,2,4-三嗪和1的高效一步合成2,4-三嗪[4,3-a]苯并咪唑衍生物
3. FLUORINATED [1,2,4]TRIAZOLO[1,5-a]PYRIMIDINES AND [1,2,4]TRIAZOLO[5,1-c][1,2,4]TRIAZINES [J] . E. N. Ulomskiy, N. R. Medvedeva, A. V. Shchepochkin, Chemistry of heterocyclic compounds . 2011,第9期

机译：氟化的[1,2,4]三唑[1,5-a]嘧啶和[1,2,4]三唑[5,1-c] [1,2,4]三嗪
4. Synthesis and properties for benzotriazole nitrogen oxides (BTzO) and tris1,2,4triazolo1,3,5triazine derivatives [C] . Yanyang Qu, Qun Zeng, Jun Wang, Seminar on New Trends in Research of Energetic Materials . 2016

机译：苯并三唑氮氧化物（BTzO）和三1,2,4三唑并1,3,5三嗪衍生物的合成及性能
5. THE SYNTHESIS OF CERTAIN NOVEL AZINE "C"-NUCLEOSIDES (PYRIMIDINE, (1,2,4)TRIAZINE, S-TRIAZINE, C-GLYCOSYL AMIDINE, AMIDRAZONE). [D] . RILEY, TIMOTHY A. 1985

机译：某些新颖的叠氮“ C”-核苷（嘧啶，（1,2,4）三嗪，S-三嗪，C-糖基A啶，酰胺基）的合成。
6. The Influence of the 1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole-4-yl Moiety on the Adenosine Receptors Affinity Profile of Pyrazolo[4,3-e][1,2,4]Triazolo[1,5-c]Pyrimidine Derivatives [O] . Stephanie Federico, Sara Redenti, Mattia Sturlese, 2010

机译：1-（3-三氟甲基苄基）-1H-吡唑-4-基对吡唑并[4,3-e] [1,2,4]三唑[1,5-]的腺苷受体亲和力的影响c]嘧啶衍生物
7. Heteroaromatization with 4-Hydroxycoumarin Part II: Synthesis of Some New Pyrano[2,3-d]pyrimidines, [1,2,4]triazolo[1,5-c]pyrimidines and Pyrimido[1,6-b]-[1,2,4]triazine Derivatives [O] . A. H. Bedair, A. H. Fakery, N. A. El-Hady, 2001

机译：4-羟基香豆素的异芳构化第二部分：一些新的吡喃并[2,3-d]嘧啶，[1,2,4]三唑并[1,5-c]嘧啶和嘧啶并[1,6-b] - [1]的合成，2,4]三嗪衍生物

Synthesis of some novel pyrazolo[1,5-a]pyrimidine, 1,2,4-triazolo[1,5-a]pyrimidine, pyrido[2,3-d]pyrimidine, pyrazolo[5,1-c]-1,2,4-triazine and 1,2,4-triazolo[5,1-c]-1,2,4-triazine derivatives incorporating a thiazolo[3,2-a]benzimidazole moiety

摘要

著录项

相似文献

相关主题

期刊订阅