Synthesis of new Schiff bases and polycyclic fused thiopyranothiazoles containing 4,6-dichloro-1,3,5-triazine moiety

Polovkovych S.V.; Karkhut A.I.; Marintsova N.G.; Lesyk R.B.; Zimenkovsky B.S.; Novikov V.P.

首页> 外文期刊>Journal of Heterocyclic Chemistry: The International Journal of Heterocyclic Chemistry >Synthesis of new Schiff bases and polycyclic fused thiopyranothiazoles containing 4,6-dichloro-1,3,5-triazine moiety

【24h】

Synthesis of new Schiff bases and polycyclic fused thiopyranothiazoles containing 4,6-dichloro-1,3,5-triazine moiety

机译：合成新的席夫碱和含有4,6-二氯-1,3,5-三嗪部分的多环稠合噻吩并噻唑

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

New aromatic aldimines, isatine substituted ketimines based on (4,6-dichloro-1,3,5-triazin-2-yl)-hydrazine scaffold and polycyclic fused thiopyranothiazoles formed using hetero-Diels-Alder reactions starting from 4-thioxo-2-thiazolidinones and 5-norbornene-2,3-dicarboxylic acid triazino-derivatives synthetic approach is described. The application of condensation and cyclocondensation reactions of N-nucleophiles and carbonyl agents for synthesis a number of biologically active triazine derivatives is reported. Screening of anticancer activity in vitro yielded the most active compounds 3a, 8b, and 8f for different cell lines.

机译：新的芳族醛亚胺，基于（4,6-dichloro-1,3,5-triazin-2-yl）-肼骨架的isatine取代的酮亚胺和使用从4-thioxo-2开始的杂Diels-Alder反应形成的多环稠合噻吩并噻唑描述了噻唑烷酮和5-降冰片烯-2，3-二羧酸三嗪基衍生物的合成方法。据报道，N-亲核试剂和羰基试剂的缩合和环缩合反应用于合成许多具有生物活性的三嗪衍生物。体外抗癌活性的筛选产生了针对不同细胞系的活性最高的化合物3a，8b和8f。

著录项

来源
《Journal of Heterocyclic Chemistry: The International Journal of Heterocyclic Chemistry》 |2013年第6期|共6页
作者
Polovkovych S.V.; Karkhut A.I.; Marintsova N.G.; Lesyk R.B.; Zimenkovsky B.S.; Novikov V.P.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类有机化学;
关键词
Synthesis; thiopyranothiazoles; aldimines;

机译：合成;吡喃并噻唑;醛亚胺;

相似文献

外文文献
中文文献
专利

1. Synthesis of new Schiff bases and polycyclic fused thiopyranothiazoles containing 4,6-dichloro-1,3,5-triazine moiety [J] . Polovkovych S.V., Karkhut A.I., Marintsova N.G., Journal of Heterocyclic Chemistry: The International Journal of Heterocyclic Chemistry . 2013,第6期

机译：合成新的席夫碱和含有4,6-二氯-1,3,5-三嗪部分的多环稠合噻吩并噻唑
2. Synthesis of semicrystalline poly(guanamine)s based on 2-substituted-4,6-dichloro-1,3,5-triazine with alpha, omega-alkylene diamines, and the formation of cyclic tetramers [J] . Shibasaki Yuji, Kotaki Tomohiro, Bito Takahiro, Polymer: The International Journal for the Science and Technology of Polymers . 2018,第期

机译：基于2-取代的-4,6-二氯-1,3,5-三嗪用α，ω-亚烷基二胺的合成半结晶聚（胍胺）S，以及环状四聚体的形成
3. Green Synthesis of Novel 2-(5-Substituted)-2,4-Dithiobiureto-4,6-Dichloro-1,3,5-Triazines [J] . Tayade D.T., Bhagwatkar A.K. Research Journal of Chemical Sciences . 2014,第9期

机译：新型2-（5-取代）-2,4-二硫代双脲-4,6-二氯-1,3,5-三嗪的绿色合成
4. 2-Chloro-4,6-dibenzyloxy-l,3,5-triazine and N-(4,6-dibenzyloxy-1,3,5-triazinyl-2)ammonium tetrafluoroborates as highly efficient coupling reagents for peptide synthesis in solution [C] . Konrad Jastrzabek, Beata Kolesinska, Michal Biaszczyk International Peptide Symposium;European Peptide Symposium . 2005

机译：2-氯-4,6-二苯苄氧基-1,3,5-三嗪和N-（4,6-二苄氧基-1,3,5-三嗪基-2）四氟硼硼酸铵作为溶液中肽合成的高效偶联试剂
5. New materials for optical sensing of explosives copolymers containing 2-vinyl-4,6-diamino-1,3,5-triazine and co-crystals of electron rich aromatic molecules and 1,3-dinitrobenzene. [D] . McNeil, Steven Keith. 2013

机译：用于爆炸物共聚物的光学传感的新材料，其中包含2-乙烯基-4,6-二氨基-1,3,5-三嗪以及富电子芳族分子和1,3-二硝基苯的共晶体。
6. Microwave Assisted Synthesis of Some New Fused 124-Triazines Bearing Thiophene Moieties With Expected Pharmacological Activity [O] . Hosam A. Saad, Mohamed M. Youssef, Mosselhi A. Mosselhi 2011

机译：微波辅助合成一些带有预期药理活性的带有噻吩基团的新型熔融124-三嗪
7. SYNTHESIS OF 2-3,3'-DI-(TERT-BUTOXYCARBONYL)-AMINODIPROPYLAMINE-4,6,-DICHLORO-1,3,5-TRIAZINE AS A MONOMER AND 1,3,5-TRIS-PIPERAZINE-TRIAZINE AS A CORE FOR THE LARGE SCALE SYNTHESIS OF MELAMINE (TRIAZINE) DENDRIMERS [O] . 2009

机译：合成2- 3,3'-二羰基羰基） - 氨基二丙基胺 -4,6 ,--二氯-1,3,5-三嗪作为单体和1,3,5-βTris-piperazine - 三嗪作为三聚氰胺的大规模合成的核心（三嗪）树枝状大分子

Synthesis of new Schiff bases and polycyclic fused thiopyranothiazoles containing 4,6-dichloro-1,3,5-triazine moiety

摘要

著录项

相似文献

相关主题

期刊订阅