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首页> 外文期刊>Journal of human nutrition and dietetics >Hypoadiponectinaemia in nonalcoholic fatty liver disease obese women is associated with infrequent intake of dietary sucrose and fatty foods
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Hypoadiponectinaemia in nonalcoholic fatty liver disease obese women is associated with infrequent intake of dietary sucrose and fatty foods

机译：非酒精性脂肪肝疾病的肥胖妇女的低脂联素血症与饮食中蔗糖和脂肪食物的摄入量少有关

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Background The present study aimed to investigate the relationship between adiponectinaemia and food intake among obese women with nonalcoholic fatty liver disease (NAFLD). Methods In total, 60 obese women were examined by abdominal ultrasound for liver steatosis and subcutaneous and visceral adiposity. A standard interview (including questions about alcohol intake, medical history and physical activity), a physical examination (including height, weight, body mass index, waist and hip circumferences, waist-to-hip ratio, and body composition) and biochemical and clinical parameters (including serum glucose and insulin, homeostatic model assessment insulin resistance, lipid profile, aminotransferases, C-reactive protein, adiponectin, leptin, resistin, tumour necrosis factor-α, interleukin-6 levels and blood pressure) were performed. Food intake was evaluated by a qualitative food frequency questionnaire. Results Twenty-four NAFLD patients and thirty-six controls were analysed. The Mann–Whitney test showed lower adiponectin levels in the liver disease group compared to controls (P?
机译：背景技术本研究旨在调查非酒精性脂肪肝病（NAFLD）肥胖女性中脂联素血症与食物摄入之间的关系。方法对60例肥胖妇女进行腹部超声检查，检查其脂肪变性，皮下和内脏脂肪。标准面试（包括有关饮酒，病史和体育锻炼的问题），体格检查（包括身高，体重，体重指数，腰围和臀围，腰臀比和身体成分）以及生化和临床进行参数检查（包括血清葡萄糖和胰岛素，体内稳态模型评估，胰岛素抵抗，脂质分布，转氨酶，C反应蛋白，脂联素，瘦素，抵抗素，肿瘤坏死因子-α，白介素6水平和血压）。通过定性食物频率问卷评估食物摄入量。结果对24例NAFLD患者和36例对照组进行了分析。 Mann-Whitney试验显示，与对照组相比，肝脏疾病组的脂联素水平较低（P <0.05）。皮尔逊相关系数表明，脂联素血症与血脂和血清肿瘤坏死因子-α呈负相关（P <=？0.05），与肥胖症的测定指标和血清瘦素呈正相关（P 0.05）。通过简单的线性回归，所有这些变量均可预测血清脂联素水平。卡方检验和Fisher精确检验表明，尽管蔗糖和脂肪食品与肝病组脂联素水平降低相关，但两组的食物摄入量均无差异（分别为P <0.05和P <0.05）。 ）以及对照组（分别为P <= 0.05和P 0.05）。结论NAFLD的低脂联素血症与饮食中的蔗糖和脂肪食物摄入有关，强调饮食在该病的发生中的重要作用。

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