Targeted Therapies in the Treatment of Cancer

Diane Twedell

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Targeted Therapies in the Treatment of Cancer

机译：癌症治疗中的靶向疗法

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Cancer is a diverse group of assorted disorders and is a major public health problem. A total of 1,372,910 new cancer cases and 570,260 cancer-related deaths are expected in the United States in 2005 (Jemal et al., 2005). Cancer can be caused by carcinogen exposure, inherited genetic factors, or a variety of yet unexplained processes. Traditionally, treatment for cancer by removing or killing the tumor cells has included surgery, radiation (external and internal), and chemotherapy. Radiation and chemotherapy treatments target rapidly dividing cells and subsequently affect both healthy cells and cancer cells, therefore causing systemic toxicities that can limit the dosing of these agents.

机译：癌症是各种各样的疾病，是主要的公共卫生问题。预计2005年美国共有1,372,910例新癌症病例和570,260例与癌症相关的死亡（Jemal等，2005）。癌症可由致癌物暴露，遗传遗传因素或各种尚未解释的过程引起。传统上，通过去除或杀死肿瘤细胞来治疗癌症的方法包括手术，放射线（外部和内部）和化学疗法。放射和化学疗法的目标是迅速分裂的细胞，随后影响健康细胞和癌细胞，因此引起全身毒性，从而限制了这些药物的剂量。

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《Journal of continuing education in nursing》 |2005年第5期|共2页
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Diane Twedell;
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机译：用于恶性肿瘤的分子靶疗法3）固体癌的分子靶标处理（1）个性化医疗的发育，使非小细胞肺癌的EGF受体成为靶标。

Targeted Therapies in the Treatment of Cancer

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