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首页> 外文期刊>Journal of health science. >Classical Conditioning of Metal lothionein Synthesis in Mice
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Classical Conditioning of Metal lothionein Synthesis in Mice

机译:小鼠金属硫蛋白合成的经典条件

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摘要

To clarify the role of metallothionein (MT), an anti-stress protein, induced by psychological stress, we carried out an experiment to determine whether hepatic MT synthesis induced by restraint stress can be classically conditioned by an olfactory odor cue of camphor. Mice were conditioned by exposure to the odor of camphor 1 hr before restraint stress and partly during restraint stress. Although exposure to the odor of camphor did not elevate hepatic MT levels in itself, the odor stimuli significantly elevated hepatic MT levels in mice conditioned for 3 days. The results indicate that MT synthesis is induced by an association of the central nervous system with psychological stress.
机译:为了阐明心理压力诱导的抗应激蛋白金属硫蛋白(MT)的作用,我们进行了一项实验,以确定由限制应激诱导的肝MT合成是否可以经典地通过樟脑的嗅觉提示来调节。在限制应激之前1小时和部分在限制应激期间通过暴露于樟脑的气味来调节小鼠。尽管暴露于樟脑的气味本身并不能提高肝MT水平,但气味刺激可显着提高适应3天的小鼠的肝MT水平。结果表明MT合成是由中枢神经系统与心理压力的关联引起的。

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