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首页> 外文期刊>Journal of industrial and engineering chemistry >Facile synthesis of monodispersed silica-coated magnetic nanoparticles
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Facile synthesis of monodispersed silica-coated magnetic nanoparticles

机译:轻松合成单分散二氧化硅包覆的磁性纳米粒子

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摘要

Silica-coated magnetic nanoparticles (MNPs) have great potential for use in field of biotechnology owing to their unique properties, which can be manipulated by an external magnetic field gradient. Herein, we describe a method for facile synthesis of monodispersed silica-coated MNPs (MNP@SiO2 NPs). Commercially available oleate-MNPs were successfully converted to polyvinylpyrrolidone-MNPs (PVP-MNPs), and then coated with silica by the modified Stober method. More than 95% of MNPs were individually coated with a silica shell; non-magnetic core silica nanoparticles (NPs) were not detected. Notably, the MNP@SiO2 NPs are highly monodispersed in size (size distribution < 2.5%) and synthesis at the scale of grams was easily obtained by a simple scale up process. Moreover, aggregation was not detected upon storage of over three months.
机译:二氧化硅涂层的磁性纳米颗粒(MNP)由于其独特的特性而具有可在生物技术领域使用的巨大潜力,可以通过外部磁场梯度来控制。在这里,我们描述了一种易于合成的单分散二氧化硅涂层的MNPs(MNP @ SiO2 NPs)的方法。将市售的油酸酯-MNP成功转化为聚乙烯吡咯烷酮-MNP(PVP-MNP),然后通过改良的Stober方法用二氧化硅进行涂覆。超过95%的MNP分别用硅石外壳包覆;未检测到非磁性核二氧化硅纳米颗粒(NPs)。值得注意的是,MNP @ SiO2 NP的尺寸高度单分散(尺寸分布<2.5%),并且通过简单的按比例放大工艺即可轻松获得克级的合成。此外,储存三个月以上未发现聚集。

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