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Albumin adsorption influence on the stability of the mesoporous zirconia suspension

机译:白蛋白吸附对介孔氧化锆悬浮液稳定性的影响

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In this paper, the stability mechanism of the mesoporous zirconia suspension in the albumin presence was described. The albumin adsorption on the zirconia surface depends on pH and ionic strength. The highest adsorption was observed at the albumin IV value (for HSA 3.1 mg/m(2)). The protein adsorption affects the suspension stability. It causes mainly its increase related to electrosteric stabilization phenomenon (pH 3, 6 and 9). At pH 4.6 there is the system destabilization due to the adsorption of the macromolecules with zero net charge. Under these conditions the greatest stability change was also observed (TSI from 8.38 to 23.97). (C) 2015 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
机译:本文描述了在白蛋白存在下中孔氧化锆悬浮液的稳定性机理。氧化锆表面上的白蛋白吸附取决于pH和离子强度。在白蛋白IV值(对于HSA 3.1 mg / m(2))处观察到最高的吸附。蛋白质吸附会影响悬浮液的稳定性。它主要导致其增加与电空间稳定现象(pH 3、6和9)有关。在pH 4.6时,由于大分子以零净电荷吸附而导致系统不稳定。在这些条件下,还观察到最大的稳定性变化(TSI从8.38到23.97)。 (C)2015韩国工业和工程化学学会。由Elsevier B.V.发布。保留所有权利。

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