Isolation of bisindole alkaloids that inhibit the cell cycle from Myxomycetes Arcyria ferruginea and Tubifera casparyi.

Nakatani S; Naoe A; Yamamoto Y; Yamauchi T; Yamaguchi N; Ishibashi M

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Isolation of bisindole alkaloids that inhibit the cell cycle from Myxomycetes Arcyria ferruginea and Tubifera casparyi.

机译：分离能抑制粘线菌，圆孢子虫和塔氏紫花病菌的细胞周期的双吲哚生物碱。

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From a myxomycete Arcyria ferruginea, dihydroarcyriarubin C (1), a new bisindole alkaloid, has been isolated together with two known bisindoles, arcyriarubin C (2) and arcyriaflavin C (3), and arcyriaflavin C (3) was also isolated from Tubifera casparyi together with arcyriaflavin B (4). Arcyriaflavin C (3) exhibited cell cycle inhibition effect at G1 and G2/M stage at 10 and 100ng/mL, respectively.

机译：从粘线菌Arcyria ferruginea中分离了一种新的双吲哚生物碱dihydroarcyriarubin C（1）以及两个已知的双吲哚，arcyriarubin C（2）和arcyriaflavin C（3），并且也从Tubifera casparyi中分离了arcyriaflavin C（3）。与阿奇黄素B（4）一起使用。 Arcyriaflavin C（3）在G1和G2 / M阶段分别以10ng / mL和100ng / mL表现出细胞周期抑制作用。

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《Bioorganic and Medicinal Chemistry Letters》 |2003年第17期|共3页
作者
Nakatani S; Naoe A; Yamamoto Y; Yamauchi T; Yamaguchi N; Ishibashi M;
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正文语种 eng
中图分类基础医学;
关键词
Carbon ion; Cell Cycle; Alkaloids; Need for isolation; Myxomycetes; 细胞周期; 生物碱类;

机译：Carbon ion;Cell Cycle;Alkaloids;Need for isolation;Myxomycetes;细胞周期;生物碱类;

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1. Isolation of bisindole alkaloids that inhibit the cell cycle from Myxomycetes Arcyria ferruginea and Tubifera casparyi. [J] . Nakatani S, Naoe A, Yamamoto Y, Bioorganic and Medicinal Chemistry Letters . 2003,第17期

机译：分离能抑制粘线菌，圆孢子虫和塔氏紫花病菌的细胞周期的双吲哚生物碱。
2. Bisindole alkaloids from myxomycetes Arcyria denudata and Arcyria obvelata [J] . Kamata K, Suetsugu T, Yamamoto Y, Journal of natural products . 2006,第8期

机译：粘菌丝虫和圆孢菌的双indole生物碱
3. New bisindole alkaloids isolated from myxomyeetes Arcyria cinerea and Lycogala epidendrum [J] . Kamata K, Kiyota M, Naoe A, Chemical and Pharmaceutical Bulletin . 2005,第5期

机译：分离自粘线菌弓形虫和表皮石蒜的新双吲哚生物碱
4. Black Cumin (Nigella sativa L.) and Awar-Awar (Ficus septica Burm. F.) Combination Extract Inhibits Proliferation and Modulates Cell Cycle on HeLa Cell [C] . Ragil Anang Santoso, Amadea Sylva Lienaningrum, Eunice Dwininta Bangun, International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering . 2019

机译：黑雀（Nigella Sativa L.）和Awar-Awar（Ficus Septica Burm.F.）组合提取物抑制了HeLa细胞上的增殖和调节细胞周期
5. Part I. Hz166, a novel γ-aminobutyric acid (A) receptor subtype-selective ligand active against neuropathic pain Part II. The first enantiospecific, stereospecific total synthesis of the C-19 methyl substituted sarpagine indole alkaloids 19(S), 20(R), 19-(S),20(R)dihydroperaksine-17-al and peraksine Part III. Application of metal-carbenoid chemistry and Brönsted acid mediated cyclization of enaminones for the rapid and efficient access to the tetracyclic (ABCE) skeleton of the Strychnos alkaloids contained in bisindole alkaloids [D] . Edwankar, Rahul V. 2010

机译：第I部分：Hz166，一种新型的对神经性疼痛有活性的γ-氨基丁酸（A）受体亚型选择性配体。 C-19甲基取代的沙雷帕金吲哚生物碱19（S），20（R），19-（S），20（R）dihydroperaksine-17-al和peraksine第三部分的第一个对映体特异性，立体定向全合成。金属类固醇化学和布朗斯台德酸介导的烯胺酮环化的应用，用于快速有效地获取双吲哚生物碱中马兜铃生物碱的四环（ABCE）骨架
6. Bisleuconothine A a bisindole alkaloid inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling [O] . Ling-Mei Kong, Tao Feng, Yuan-Yuan Wang, 2016

机译：Bisleuconothine A一种双吲哚生物碱在体外和体内靶向Wnt信号传导抑制结直肠癌细胞
7. New Bisindole Alkaloids Isolated from Myxomycetes Arcyria cinerea and Lycogala epidendrum [O] . Kazuaki Kamata, Makiko Kiyota, Ayano Naoe, 2005

机译：从骨髓瘤甲克里斯氏菌和枸杞症的新的双吲哚生物碱

Isolation of bisindole alkaloids that inhibit the cell cycle from Myxomycetes Arcyria ferruginea and Tubifera casparyi.

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