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首页> 外文期刊>Journal of interventional cardiac electrophysiology: an international journal of arrhythmias and pacing >Outcomes after endocarditis or device infection in patients with left ventricular epicardial leads versus coronary sinus leads
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Outcomes after endocarditis or device infection in patients with left ventricular epicardial leads versus coronary sinus leads

机译：左室心外膜导联与冠状窦导联的患者心内膜炎或装置感染后的结果

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摘要

Background: There is scant data about outcomes in patients with left ventricular epicardial (LVE) leads who develop endocarditis or device-related infection. Objective: This retrospective study evaluated mortality and recurrence of infection among patients with LVE leads in comparison to patients with endovascular coronary sinus (CS) leads after the development of endocarditis or device-related infection. Methods: Patients with cardiac resynchronization therapy (CRT) devices who developed endocarditis or pocket infection over 5 years at Cleveland Clinic were included in the study. The groups were all patients with LVE leads versus CRT devices without epicardial leads that developed endocarditis or pocket infection. Mortality was assessed using the Social Security Death Index and re-infection was assessed by reviews of the medical record. Results: Prospective extraction of the CRT device and leads occurred among all 50 patients with CS leads and 8 of the 14 patients with LVE leads. The survival rate was 92.9 versus 92 % and freedom from re-infection rate was 64.3 versus 80 % in the patients with LVE leads versus CS leads, respectively, over 1 year (P value=0.918 and 0.226, respectively). At 3 years, the survival rate in LVE lead group was 92.9 % and freedom from re-infection rate was 64.3 % in comparison to survival rate of 90 % and freedom from re-infection rate of 68 % in the CS group (P value=0.751 and 0.798, respectively). Conclusion: After development of endocarditis or pocket infection, no statistically significant differences were seen in mortality, or recurrent infection between patients with LVE leads and those with CS leads.
机译：背景：关于发生心内膜炎或与设备相关的感染的左心室心外膜（LVE）导联患者的预后数据很少。目的：这项回顾性研究评估了心内膜炎或与设备相关的感染后，LVE导线患者与血管内冠状窦（CS）导线患者的死亡率和感染复发。方法：研究包括在克利夫兰诊所进行了5年以上的心内再同步治疗（CRT）装置的心内膜炎或口袋感染的患者。这些组都是LVE导联vs CRT装置而无心外膜导联发展为心内膜炎或口袋感染的患者。使用社会保障死亡指数评估死亡率，并通过检查病历评估再次感染。结果：所有50例CS导线患者和14例LVE导线患者中的8例均发生了CRT装置和导线的前瞻性拔除。 LVE导联与CS导联的患者在1年内的存活率分别为92.9％对92％，无再感染率分别为64.3％对80％（P值分别为0.918和0.226）。与CS组的90％的生存率和68％的无再感染率相比，LVE铅组在3年时的生存率为92.9％，无再次感染率为64.3％（P =分别为0.751和0.798）。结论：心内膜炎或口袋感染发生后，LVE导联患者和CS导联患者之间的死亡率或复发感染无统计学差异。

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