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首页> 外文期刊>Journal of Internal Medicine >The incidence and survival of acute de novo leukaemias in Estonia and in a well-defined region of western Sweden during 1982-1996: a survey of patients aged >/=65 years.
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The incidence and survival of acute de novo leukaemias in Estonia and in a well-defined region of western Sweden during 1982-1996: a survey of patients aged >/=65 years.

机译：1982年至1996年期间，爱沙尼亚和瑞典西部一个明确地区的急性新发白血病的发生率和存活率：对年龄≥65岁的患者进行的调查。

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Abstract. Luik E, Palk K, Everaus H, Varik M, Aareleid T, Wennstrom L, Juntikka E-L, Safai-Kutti S, Stockelberg D, Holmberg E, Kutti J (Clinic of Hematology and Oncology, Tartu University Clinics, Tartu; Estonian Cancer Registry, North Estonian Regional Hospital, Tallinn; National Institute for Health Development, Tallinn, Estonia; and Sahlgrenska University Hospital, Goteborg, Sweden). The incidence and survival of acute de novo leukaemias in Estonia and in a well-defined region of western Sweden during 1982-1996: a survey of patients aged >/=65 years. J Intern Med 2004; 256: 79-85.Objectives. To compare the incidence and survival of acute de novo leukaemias with particular reference to political/socio-economic and environmental factors in two neighbouring countries over the three 5-year periods (1982-1996). Patients. The present report covers only patients diagnosed when aged >/=65 years. Setting. A well-defined area of Sweden, the so-called Western Swedish Health Care Region and Estonia. Population-wise, the western Swedish Region and Estonia are very similar; area-wise they are also well comparable. Results. The number of acute de novo leukaemias was quite dissimilar in the two countries (Estonia, n = 137, Sweden, n = 354). The age standardized incidence rates regarding the total number of acute de novo leukaemias was 5.31 per 100 000 inhabitants/year for Estonia and 7.99 for Sweden, this difference being statistically significant. However, the difference was merely attributable to incidence rates as regards acute myeloblastic leukaemias (AML); on the contrary, differences as regards acute lymphoblastic leukaemias (ALL) and non-classifiable, undifferentiated or biphenotypic acute leukaemias (uAL) were negligible. The relative survival for the total material of patients was significantly higher for Swedish when compared with Estonian patients (P < 0.001). Thus, the relative survival for the total material of patients aged >/=65 years in Estonia at 1 year was 8.5% and at 3 years 3.5% respectively. The corresponding figures for the Swedish patients were considerably higher, 22.7 and 7.7% respectively. This difference, however, applied only for patients with AML (P < 0.001), whereas the results for patients with ALL and uAL were equally dismal. Conclusion. The results clearly reflect how political and socio-economic factors may influence the survival of acute leukemia patients in two neighbouring countries.
机译：抽象。 Luik E，Palk K，Everaus H，Varik M，Aareleid T，Wennstrom L，Juntikka EL，Safai-Kutti S，Stockelberg D，Holmberg E，Kutti J（塔尔图大学诊所血液学和肿瘤学，塔尔图;爱沙尼亚癌症登记处，塔林北爱沙尼亚地区医院，爱沙尼亚塔林国家卫生发展研究所和瑞典哥德堡萨尔格伦斯卡大学医院。 1982年至1996年期间，爱沙尼亚和瑞典西部一个明确地区的急性新发白血病的发生率和存活率：对年龄≥65岁的患者进行了调查。 J Intern Med 2004; 256：79-85。为了比较急性新白血病的发病率和生存率，特别是在三个五年期间（1982-1996年）中两个邻国的政治/社会经济和环境因素。耐心。本报告仅涵盖年龄≥65岁的被诊断患者。设置。瑞典的一个定义明确的地区，即所谓的瑞典西部卫生保健区和爱沙尼亚。在人口方面，瑞典西部地区和爱沙尼亚非常相似。从面积上看，它们也具有可比性。结果。在这两个国家，急性新发白血病的数量完全不同（爱沙尼亚，n = 137，瑞典，n = 354）。关于急性新白血病总数的年龄标准化发生率，爱沙尼亚为每10万居民每年5.31，瑞典为7.99，这一差异具有统计学意义。但是，差异仅归因于急性粒细胞白血病（AML）的发病率;相反，急性淋巴细胞白血病（ALL）和不可分类，未分化或双表型急性白血病（uAL）的差异可以忽略不计。与爱沙尼亚患者相比，瑞典患者的全部材料的相对存活率明显更高（P <0.001）。因此，爱沙尼亚年龄≥65岁的患者的全部材料在1年时的相对生存率分别为8.5％和3年时3.5％。瑞典患者的相应数字更高，分别为22.7和7.7％。但是，这种差异仅适用于AML患者（P <0.001），而ALL和uAL患者的结果同样令人沮丧。结论。结果清楚地反映了政治和社会经济因素如何影响两个邻国急性白血病患者的生存。

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