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首页> 外文期刊>Journal of Korean medical science >Magnetoencephalography in pediatric lesional epilepsy surgery
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Magnetoencephalography in pediatric lesional epilepsy surgery

机译：脑磁图在小儿​​病灶性癫痫手术中的应用

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摘要

This study was performed to assess the usefulness of magnetoencephalography (MEG) as a presurgical evaluation modality in Korean pediatric patients with lesional localizationrelated epilepsy. The medical records and MEG findings of 13 pediatric patients (6 boys and 7 girls) with localization-related epilepsy, who underwent epilepsy surgery at Seoul National University Children's Hospital, were retrospectively reviewed. The hemispheric concordance rate was 100% (13/13 patients). The lobar or regional concordance rate was 77% (10/13 patients). In most cases, the MEG spike sources were clustered in the proximity of the lesion, either at one side of the margin (nine patients) or around the lesion (one patient); clustered spike sources were distant from the lesion in one patient. Among the patients with clustered spike sources near the lesion, further extensions (three patients) and distal scatters (three patients) were also observed. MEG spike sources were well lateralized and localized even in two patients without focal epileptiform discharges in the interictal scalp electroencephalography. Ten patients (77%) achieved Engel class I postsurgical seizure outcome. It is suggested that MEG is a safe and useful presurgical evaluation modality in pediatric patients with lesion localization-related epilepsy.
机译：这项研究的目的是评估磁脑电图（MEG）作为韩国儿科患者病灶定位相关性癫痫的术前评估方法的有效性。回顾性地回顾了在首尔国立大学儿童医院接受癫痫手术的13例小儿（与男孩有关的局部疾病）的病历和MEG检查结果（6例男孩和7例女孩）。半球一致性率为100％（13/13例）。大叶或区域一致率为77％（10/13例）。在大多数情况下，MEG尖峰源聚集在病变附近，在边缘的一侧（9例）或在病变周围（1例）。一名患者的聚集的尖峰源远离病变。在病灶附近有聚集的尖峰源的患者中，还观察到进一步的扩展（3例）和远端散射（3例）。即使在两名在发作性头皮脑电图中没有局灶性癫痫样放电的患者中，MEG尖峰信号源也可以很好地横向化和定位。十名患者（77％）达到了恩格尔I类手术后癫痫发作的结局。提示MEG对于患病部位相关性癫痫的小儿患者是一种安全而有用的术前评估方法。

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