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首页> 外文期刊>Journal of Korean medical science >Clinical implication of surgical resection for the rare cardiac tumors involving heart and great vessels
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Clinical implication of surgical resection for the rare cardiac tumors involving heart and great vessels

机译:手术切除对累及心脏和大血管的罕见心脏肿瘤的临床意义

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摘要

This study aimed to investigate the clinical implication of surgical resection for the malignancies of heart and great vessels. Between January 2001 and May 2011, a retrospective review of the results in 12 patients was conducted. There were 6 patients with primary cardiac tumor including leiomyosarcoma, angiosarcoma, undifferentiated type sarcoma and malignant fibrous histiocytoma. The remaining 6 patients had the metastatic tumors or adjacent invasion to the heart and great vessels. Six of seven patients who underwent complete resection had no evidence of recurrence. However, four of five patients who underwent incomplete resection or biopsy showed local recurrence or distant metastasis of residualtumor, and one of them required reoperation for recurred tumor. Inhospital mortality was 8.3% and the mean survival of all pa ients was 22.2 ± 6.1 months. Survival of the incomplete resection group, except for the two biopsy cases, was 25.9 ± 7.9 months, and there was no mortality in the complete resection group. Therefore, clinical outcomes in patientswho had malignancies of the heart and great vessels may be improved when the aggressive and complete resection, or possible debulking for palliation, was performed. Moreover, adjuvant multimodality therapy may be imperative to prevent recurrence or metastasis, and to provide improved survival.
机译:这项研究旨在调查外科切除对心脏和大血管恶性肿瘤的临床意义。在2001年1月至2011年5月之间,对12例患者的结果进行了回顾性回顾。有6例原发性心脏肿瘤患者,包括平滑肌肉瘤,血管肉瘤,未分化型肉瘤和恶性纤维组织细胞瘤。其余6例患者有转移性肿瘤或侵犯心脏和大血管。接受完全切除的7例患者中有6例没有复发的证据。然而,接受不完全切除或活检的五位患者中有四位表现出局部复发或残余肿瘤的远处转移,其中一位需要复发。住院死亡率为8.3%,所有患者的平均生存期为22.2±6.1个月。除两名活检病例外,不完全切除组的生存时间为25.9±7.9个月,完全切除组无死亡。因此,如果进行积极而完整的切除术,或可能减轻肿块的缓解程度,则患有心脏恶性肿瘤和大血管的患者的临床结局可能会得到改善。此外,辅助性多模态治疗可能对于预防复发或转移以及提高生存率势在必行。

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