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首页> 外文期刊>Journal of Korean medical science >The risk of obstructive lung disease by previous pulmonary tuberculosis in a country with intermediate burden of tuberculosis.
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The risk of obstructive lung disease by previous pulmonary tuberculosis in a country with intermediate burden of tuberculosis.

机译:在结核病负担中等的国家中,先前的肺结核会导致阻塞性肺部疾病的风险。

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We evaluated the effects of previous pulmonary tuberculosis (TB) on the risk of obstructive lung disease. We analyzed population-based, the Second Korea National Health and Nutrition Examination Survey 2001. Participants underwent chest X-rays (CXR) and spirometry, and qualified radiologists interpreted the presence of TB lesion independently. A total of 3,687 underwent acceptable spirometry and CXR. Two hundreds and ninety four subjects had evidence of previous TB on CXR with no subjects having evidence of active disease. Evidence of previous TB on CXR were independently associated with airflow obstruction (adjusted odds ratios [OR] = 2.56 [95% CI 1.84-3.56]) after adjustment for sex, age and smoking history. Previous TB was still a risk factor (adjusted OR = 3.13 [95% CI 1.86-5.29]) with exclusion of ever smokers or subjects with advanced lesion on CXR. Among never-smokers, the proportion of subjects with previous TB on CXR increased as obstructive lung disease became more severe. Previous TB is an independent risk factor for obstructive lung disease, even if the lesion is minimal and TB can be an important cause of obstructive lung disease in never-smokers. Effort on prevention and control of TB is crucial in reduction of obstructive lung disease, especially in countries with more than intermediate burden of TB.
机译:我们评估了先前的肺结核(TB)对阻塞性肺疾病风险的影响。我们分析了以人群为基础的《第二次韩国全国健康与营养检查调查2001》。参与者对他们进行了胸部X射线(CXR)和肺活量测定,合格的放射科医生独立解释了结核病的存在。共有3,687人接受了可接受的肺活量测定和CXR。 294名受试者在CXR上曾有结核病的证据,而没有受试者患有活动性疾病。在调整了性别,年龄和吸烟史后,CXR上先前的结核病证据与气流阻塞(校正比值比[OR] = 2.56 [95%CI 1.84-3.56])独立相关。先前的结核病仍是危险因素(校正OR = 3.13 [95%CI 1.86-5.29]),排除了吸烟者或CXR病灶加重的患者。在永不吸烟者中,随着阻塞性肺部疾病的恶化,先前患有CXR结核病的患者比例增加。既往结核病是阻塞性肺疾病的独立危险因素,即使病变极小且结核病也可能是从不吸烟者阻塞性肺病的重要原因。预防和控制结核病的努力对于减少阻塞性肺疾病至关重要,特别是在结核病负担中等的国家。

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