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首页> 外文期刊>Journal of Korean medical science >Clinical characteristics of 75 patients with leukemia cutis
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Clinical characteristics of 75 patients with leukemia cutis

机译：75例皮肤角质病的临床特点

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Leukemia cutis (LC) is defined as a neoplastic leukocytic infiltration of the skin. Few clinical studies are available on recent trends of LC in Korea. The purpose of this study was to analyze the clinical features and prognosis of LC in Korea and to compare findings with previous studies. We performed a retrospective study of 75 patients with LC and evaluated the patients'age and sex, clinical features and skin lesion distribution according to the type of leukemia, interval between the diagnosis of leukemia and the development of LC, and prognosis. The male to female ratio was 2:1, and the mean age at diagnosis was 37.6 yr. The most common cutaneous lesions were nodules. The most commonly affected site was the extremities in acute myelocytic leukemia and chronic myelocytic leukemia except for acute lymphocytic leukemia. Compared with previous studies, there was an increasing tendency in the proportion of males and nodular lesions, and LC most often occurred in the extremities. The prognosis of LC was still poor within 1 yr, which was similar to the results of previous studies. These results suggest that there is a difference in the clinical characteristics and predilection sites according to typeof leukemia.
机译：皮肤角质层白血病（LC）定义为皮肤肿瘤性白细胞浸润。关于韩国​​LC近期趋势的临床研究很少。这项研究的目的是分析韩国LC的临床特征和预后，并将其发现与以前的研究进行比较。我们对75例LC患者进行了回顾性研究，并根据白血病的类型，白血病诊断与LC的发展之间的间隔以及预后评估了患者的年龄和性别，临床特征和皮肤病变分布。男女之比为2：1，诊断时的平均年龄为37.6岁。最常见的皮肤病变是结节。受累最严重的部位是急性髓细胞性白血病和慢性粒细胞性白血病的肢体，急性淋巴细胞性白血病除外。与以前的研究相比，男性和结节性病变的比例呈上升趋势，LC最常见于四肢。 LC的预后在1年内仍然很差，这与以前的研究结果相似。这些结果表明，根据白血病的类型，临床特征和患病部位存在差异。

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