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首页> 外文期刊>Journal of Korean medical science >Predictors and clinical impact of inappropriate implantable cardioverter-defibrillator shocks in Korean patients
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Predictors and clinical impact of inappropriate implantable cardioverter-defibrillator shocks in Korean patients

机译：韩国患者不适当的植入式心脏复律除颤器电击的预测因素和临床影响

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摘要

Limited data are available on inappropriate shocks in Korean patients implanted with an implantable cardioverter-defibrillator (ICD). We investigated the impact of inappropriate shocks on clinical outcomes. This retrospective, single-center study included 148 patients treated between October 1999 and June 2011. The primary outcome was a composite event of all-cause mortality or hospitalization for any cardiac reason. The median followup duration was 29 months (interquartile range: 8 to 53). One or more inappropriate shocks occurred in 34 (23.0%) patients. A history of atrial fibrillation was the only independent predictor of inappropriate shock (hazard ratio [HR]: 4.16, 95% confidence interval [CI]: 1.89-9.15, P < 0.001). Atrial fibrillation was the most common cause of inappropriate shock (67.7%), followed by supraventricular tachycardia (23.5%), and abnormal sensing (8.8%). A composite event of all-cause mortality or hospitalizations for any cardiac reason during follow-up was not significantly different between patients with or without inappropriate shock (inappropriate shock vs no inappropriate shock: 35.3% vs 35.4%, adjusted HR: 1.06, 95% CI: 0.49-2.29, P = 0.877). Inappropriate shocks do not affect clinical outcomes in patients implanted with an ICD, although the incidence of inappropriate shocks is high.
机译：关于韩国​​植入了植入式心脏复律除颤器（ICD）的患者的不当电击的可用数据有限。我们调查了不适当的电击对临床结果的影响。这项回顾性，单中心研究纳入了1999年10月至2011年6月间接受治疗的148例患者。主要结果是由于任何心脏原因导致的全因死亡率或住院治疗的复合事件。中位随访时间为29个月（四分位间距：8到53）。 34（23.0％）位患者发生了一次或多次不适当的电击。心房颤动史是不适当电击的唯一独立预测因子（危险比[HR]：4.16，95％置信区间[CI]：1.89-9.15，P <0.001）。房颤是引起不适当电击的最常见原因（67.7％），其次是室上性心动过速（23.5％）和感觉异常（8.8％）。不论是否有不适当电击的患者，随访期间因任何心脏原因导致的全因死亡率或住院的复合事件之间无显着差异（不适当电击与无不适当电击：35.3％vs 35.4％，调整后HR：1.06，95％ CI：0.49-2.29，P ＝ 0.877）。尽管不适当的电击的发生率很高，但不适当的电击不会影响植入ICD的患者的临床结局。

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