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首页> 外文期刊>Journal of Leukocyte Biology: An Official Publication of the Reticuloendothelial Society >17beta-Estradiol: a novel hormone for improving immune and cardiovascular responses following trauma-hemorrhage.
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17beta-Estradiol: a novel hormone for improving immune and cardiovascular responses following trauma-hemorrhage.

机译：17β-雌二醇：一种新型激素，可改善创伤性出血后的免疫和心血管反应。

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摘要

17beta-Estradiol (i.e., estrogen or E2) is a female sex steroid, which plays an essential role in female reproductive physiology. However, several lines of evidence indicate that in addition to its role in reproductive physiology, E2 is critical for maintaining many other organ functions in stress conditions. These include immune, cardiovascular, and neuronal functions, as well as regulation of skin, bone, and lipid metabolism. Studies have examined the role of E2 as an adjunct in post-trauma responses, and this article will review whether E2 as an adjunct to fluid resuscitation following trauma-hemorrhage plays any role in improving/restoring immune and cardiovascular functions.
机译：17β-雌二醇（即雌激素或E2）是女性性类固醇，在女性生殖生理中起着至关重要的作用。然而，一些证据表明，E2除了在生殖生理中的作用外，对于在压力条件下维持许多其他器官功能也至关重要。这些包括免疫，心血管和神经元功能，以及皮肤，骨骼和脂质代谢的调节。研究已经检查了E2在创伤后反应中的辅助作用，本文将回顾E2作为创伤性出血后液体复苏的辅助物是否在改善/恢复免疫和心血管功能中起任何作用。

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