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首页> 外文期刊>Journal of Leukocyte Biology: An Official Publication of the Reticuloendothelial Society >The immunobiology of eosinophils-it's a whole new world out there: an interview with Dr. Peter F. Weller
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The immunobiology of eosinophils-it's a whole new world out there: an interview with Dr. Peter F. Weller

机译:嗜酸性粒细胞的免疫生物学-这是一个全新的世界:Peter F. Weller博士访谈

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摘要

The manuscript "Eosinophils mediate early alum adjuvant-elicited B cell priming and IgM production" was selected as a Pivotal Advance because it addresses an important and novel function of mouse eosinophils, Although eosinophils are traditionally perceived as end-stage degranulating cells, the results of numerous recent studies have broadened our perspective on eosinophil effector function, In this work, Wang and Weller demonstrate that eosinophils stimulate early B cell responses, notably the production of antigen-specific IgM.
机译:手稿“嗜酸性粒细胞介导明矾佐剂引起的早期B细胞启动和IgM产生”被选为重要进展,因为它解决了小鼠嗜酸性粒细胞的重要且新颖的功能,尽管传统上嗜酸性粒细胞被认为是末期脱粒细胞,但是最近的许多研究已经拓宽了我们对嗜酸性粒细胞效应子功能的认识。在这项工作中,Wang和Weller证明了嗜酸性粒细胞刺激早期B细胞反应,特别是抗原特异性IgM的产生。

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