CSF-1, IGF-1, and the control of postnatal growth and development.

Gow DJ; Sester DP; Hume DA

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CSF-1, IGF-1, and the control of postnatal growth and development.

机译：CSF-1，IGF-1和产后生长发育的控制。

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Growth hormone controls somatic growth in mammals by regulating the production of IGF-1, which is predominantly made by the liver. The development of cells within the MPS is controlled by the lineage-specific growth factor M-CSF (CSF-1). In this review, we summarize the role of CSF-1-dependent macrophages in somatic growth and organogenesis. We propose that macrophages are the major extrahepatic source of IGF-1 and that a surge of CSF-1 production contributes to the control of postnatal growth and organ maturation. Accordingly, CSF-1 may be considered a part of the GH/IGF-1 axis.

机译：生长激素通过调节主要由肝脏产生的IGF-1的产生来控制哺乳动物的体细胞生长。 MPS中细胞的发育受谱系特异性生长因子M-CSF（CSF-1）的控制。在这篇综述中，我们总结了依赖CSF-1的巨噬细胞在体细胞生长和器官发生中的作用。我们建议巨噬细胞是IGF-1的主要肝外来源，并且CSF-1产量的激增有助于控制产后生长和器官成熟。因此，可以将CSF-1视为GH / IGF-1轴的一部分。

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《Journal of Leukocyte Biology: An Official Publication of the Reticuloendothelial Society》 |2010年第3期|共7页
作者
Gow DJ; Sester DP; Hume DA;
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正文语种 eng
中图分类基础医学;
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1. CSF-1, IGF-1, and the control of postnatal growth and development. [J] . Gow DJ, Sester DP, Hume DA Journal of Leukocyte Biology: An Official Publication of the Reticuloendothelial Society . 2010,第3期

机译：CSF-1，IGF-1和产后生长发育的控制。
2. Septoclast Deficiency Accompanies Postnatal Growth Plate Chondrodysplasia in the Toothless (tl) Osteopetrotic, Colony-Stimulating Factor-1 (CSF-1)-Deficient Rat and Is Partially Responsive to CSF-1 Injections [J] . Alison Gartland, April Mason-Savas, Meiheng Yang, American Journal of Pathology . 2009,第6期

机译：Septoclast缺乏症伴随无齿（tl）骨质，集落刺激因子1（CSF-1）缺乏症大鼠的产后生长板软骨发育不良，对CSF-1注射有部分反应
3. Septoclast deficiency accompanies postnatal growth plate chondrodysplasia in the toothless (tl) osteopetrotic, colony-stimulating factor-1 (CSF-1)-deficient rat and is partially responsive to CSF-1 injections. [J] . Gartland A, Mason Savas A, Yang American Journal of Pathology: Official Publication of the American Association of Pathologists . 2009,第6期

机译：破骨细胞缺乏症伴随无齿（t1）骨质疏松，集落刺激因子-1（CSF-1）缺乏症大鼠的产后生长板软骨发育不良，对CSF-1注射有部分反应。
4. Changes in the growth hormone/insulin-like growth factor-I axis during the early postnatal development of Tibet piglets (a typical mini pig) [C] . Q.Hu, M.J.Bo, P.Kang, Progress in functional amino acids and carbohydrates for animal production . 2009

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5. Simulation of the effects of carbon dioxide, climate change, and controlled environments on wheat growth and development. [D] . Tubiello, Francesco Nicola. 1995

机译：模拟二氧化碳，气候变化和受控环境对小麦生长发育的影响。
6. Septoclast Deficiency Accompanies Postnatal Growth Plate Chondrodysplasia in the Toothless (tl) Osteopetrotic Colony-Stimulating Factor-1 (CSF-1)-Deficient Rat and Is Partially Responsive to CSF-1 Injections [O] . Alison Gartland, April Mason-Savas, Meiheng Yang, 2009

机译：Septoclast缺乏症伴随无齿（tl）骨质集落刺激因子1（CSF-1）缺乏症大鼠的产后生长板软骨发育不良对CSF-1注射有部分反应
7. Septoclast Deficiency Accompanies Postnatal Growth Plate Chondrodysplasia in the Toothless (tl) Osteopetrotic, Colony-Stimulating Factor-1 (CSF-1)-Deficient Rat and Is Partially Responsive to CSF-1 Injections [O] . Gartland, Alison, Mason-Savas, April, Yang, Meiheng, 2009

机译：Septoclast缺乏症伴随无齿（tl）骨质，集落刺激因子1（CSF-1）缺乏大鼠的产后生长板软骨发育不良，对CSF-1注射有部分反应

CSF-1, IGF-1, and the control of postnatal growth and development.

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