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首页> 外文期刊>Journal of Avian Medicine and Surgery >Long-term Management of Thymic Lymphoma in a Java Sparrow (Lonchura oryzivora)
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Long-term Management of Thymic Lymphoma in a Java Sparrow (Lonchura oryzivora)

机译：爪麻雀（Lonchura oryzivora）胸腺淋巴瘤的长期管理

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摘要

A 4-year-old Java sparrow (Lonchura oryzivora) was diagnosed with thymic lymphoma based on the results of histopathologic evaluation and immunohistochemical staining of a Tru-cut biopsy sample. The bird was treated with chlorambucil (2 mg/kg PO) twice per week for the first 18 weeks, and the mass size, activity level, appetite, bowel function, and body weight were monitored weekly. At week 19, the bird became ill and anorexic, and the chlorambucil treatment was discontinued. The neoplasm grew rapidly during weeks 20 and 21, and the chlorambucil treatment was resumed at week 23. At week 28, the bird's overall condition worsened and the chlorambucil treatment was discontinued because no additional reduction in mass size had occurred. At week 29, prednisolone (2.2 mg/kg) was administered orally every 12 h for 31 weeks. At week 61, the patient became acutely ill, exhibiting anorexia and a decreased level of physical activity, and the owner elected to euthanatize the bird. This is the first report of long-term management of thymic lymphoma in a Java sparrow.
机译：根据组织病理学评估结果和Tru-cut活检样本的免疫组织化学染色结果，将4岁的Java麻雀（Lonchura oryzivora）诊断为胸腺淋巴瘤。在头18周内，每周两次用苯丁酸氮芥（2 mg / kg PO）处理该家禽，并每周监测其质量大小，活动水平，食欲，肠功能和体重。在第19周，这只鸟生病了并且厌食，并且苯丁酸氮芥的治疗被终止。肿瘤在第20周和第21周迅速生长，并在第23周恢复苯丁酸氮芥治疗。在第28周，由于总体质量未发生进一步降低，该家禽的总体状况恶化，并停止了苯丁酸氮芥治疗。在第29周，每12小时口服泼尼松龙（2.2 mg / kg），持续31周。在第61周，患者患了重病，表现出厌食症和体力活动水平下降，主人选择对这只鸟实施安乐死。这是爪哇麻雀的胸腺淋巴瘤长期治疗的首次报道。

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