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首页> 外文期刊>Journal of magnetic resonance >PERFIDI filters to suppress and/or quantify relaxation time components in multi-component systems: An example for fat-water systems
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PERFIDI filters to suppress and/or quantify relaxation time components in multi-component systems: An example for fat-water systems

机译：PERFIDI过滤器可抑制和/或量化多组分系统中的弛豫时间组分：脂肪水系统的示例

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摘要

Parametrically Enabled Relaxation FIlters with Double and multiple Inversion (PERFIDI) is an experimental NMR/MRI technique devised to analyze samples/voxels characterized by multi-exponential longitudinal relaxation. It is based on a linear combination of NMR sequences with suitable preambles composed of inversion pulses. Given any standard NMR/MRI sequence, it permits one to modify it in a way which will attenuate, in a predictable manner and before data acquisition, signals arising from components with different r rates (r = 1/T_1). Consequently, it is possible to define relatively simple protocols to suppress and/or to quantify signals of different components. This article describes a simple way to construct low-pass, high-pass and band-pass PERFIDI filters. Experimental data are presented in which the method has been used to separate fat and water proton signals. We also present a novel protocol for very fast determination of the ratio between the fat signal and the total signal which avoids any time-consuming magnetization recovery multi-array data acquisition. The method has been validated also for MRI, producing well T _1-contrasted images.
机译：具有双反转和多重反转的参数化松弛滤波器（PERFIDI）是一种实验NMR / MRI技术，旨在分析具有多指数纵向松弛特性的样本/体素。它基于NMR序列与由反演脉冲组成的合适前同步码的线性组合。给定任何标准的NMR / MRI序列，它允许人们对其进行修改，从而以可预测的方式并在数据采集之前衰减由具有不同r速率（r = 1 / T_1）的分量产生的信号。因此，可以定义相对简单的协议来抑制和/或量化不同分量的信号。本文介绍了一种构造低通，高通和带通PERFIDI滤波器的简单方法。提出了实验数据，其中该方法已用于分离脂肪和水质子信号。我们还提出了一种新颖的协议，可以非常快速地确定脂肪信号与总信号之间的比率，从而避免了任何费时的磁化恢复多阵列数据采集。该方法也已通过MRI验证，可产生T _1对比度良好的图像。

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