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首页> 外文期刊>Biophysical Chemistry: An International Journal Devoted to the Physical Chemistry of Biological Phenomena >BIRTH OF THE MACROMOLECULE
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BIRTH OF THE MACROMOLECULE

机译：大分子的诞生

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摘要

The science of chemistry has made considerable advances over the last few hundred years in the characterization of ''small'' molecules which can be purified and studied by melting, distillation, crystallization and solubility in various liquids. When the study of ''large'' natural and biological molecules, limited in these properties, rose in significance at the turn of the century, it was first attempted to explain their properties by the concepts of colloid chemistry of aggregation and complex formation. The struggle for the acceptance of the concept of the natural or biological covalently bonded macromolecule, as recalled by Herman Mark, is one of the interesting chapters in recent science history. A specific phase in the establishment of the macromolecular concept centered around the development by The Svedberg of the analytical ultracentrifuge, a versatile tool of highly practical and profound thermodynamic significance. [References: 62]
机译：在过去的几百年中，化学科学在“小”分子的表征方面取得了长足的进步，这些小分子可以通过熔融，蒸馏，结晶和在各种液体中的溶解度进行纯化和研究。当对这些性质有限的“大”天然和生物分子的研究在世纪之初变得意义重大时，人们首先尝试通过聚集和复合物形成的胶体化学概念来解释其性质。赫曼·马克（Herman Mark）回忆说，为接受天然或生物共价键合的大分子的概念而进行的斗争是最近科学史上有趣的一章。建立大分子概念的一个特定阶段围绕着Svedberg对分析超速离心机的开发，这是一种具有高度实用性和深远热力学意义的多功能工具。 [参考：62]

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