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首页> 外文期刊>Journal of magnetic resonance imaging: JMRI >Endorectal diffusion-weighted imaging in prostate cancer to differentiate malignant and benign peripheral zone tissue.
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Endorectal diffusion-weighted imaging in prostate cancer to differentiate malignant and benign peripheral zone tissue.

机译：前列腺癌的直肠内扩散加权成像可区分恶性和良性外周带组织。

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PURPOSE: To determine if the apparent diffusion coefficient (ADC) can discriminate benign from malignant peripheral zone (PZ) tissue in patients with biopsy-proven prostate cancer that have undergone endorectal diffusion-weighted imaging (DWI) of the prostate. MATERIALS AND METHODS: Ten patients with prostate cancer underwent endorectal magnetic resonance imaging (MRI) in addition to DWI. A two-dimensional grid was placed over the axial images, and each voxel was graded by a 4-point rating scale to discriminate nonmalignant from malignant PZ tissue based on MR images alone. ADC was then determined for each voxel and plotted for nonmalignant and malignant voxels for the entire patient set. Second, with the radiologist aware of biopsy locations, any previously assigned voxel grade that was inconsistent with biopsy data was regrouped and ADCs were replotted. RESULTS: For the entire patient set, without and with knowledge of the biopsy data, the mean ADCs for nonmalignant and malignant tissue were 1.61 +/-0.27 and 1.34 +/- 0.38 x 10(-3) mm(2)/second (P = 0.002) and 1.61 +/- 0.26 and 1.27 +/- 0.37 x 10(-3) mm(2)/second (P = 0.0005), respectively. CONCLUSION: DWI of the prostate is possible with an endorectal coil. The mean ADC for malignant PZ tissue is less than nonmalignant tissue, although there is overlap in individual values. J. Magn. Reson. Imaging 2004;20:654-661. Copyright 2004 Wiley-Liss, Inc.
机译：目的：确定经表皮扩散加权成像（DWI）活检证实的前列腺癌患者的表观扩散系数（ADC）是否能将其与恶性外周区（PZ）组织区分开。材料与方法：除DWI外，十名前列腺癌患者还接受了直肠内磁共振成像（MRI）。将二维网格放置在轴向图像上，并通过4点等级量表对每个体素进行分级，以仅基于MR图像将恶性与恶性PZ组织区分开。然后确定每个体素的ADC并绘制整个患者组的非恶性和恶性体素。其次，在放射科医生了解活检位置的情况下，重新分配了任何先前与活检数据不一致的体素等级，并重新绘制了ADC。结果：在整个患者组中，在不了解活检数据的情况下，非恶性和恶性组织的平均ADC为1.61 +/- 0.27和1.34 +/- 0.38 x 10（-3）mm（2）/秒（ P = 0.002）和1.61 +/- 0.26和1.27 +/- 0.37 x 10（-3）mm（2）/秒（P = 0.0005）。结论：直肠内线圈可导致前列腺DWI。尽管单个值存在重叠，但恶性PZ组织的​​平均ADC小于非恶性组织。 J.Magn。雷森成像2004; 20：654-661。版权所有2004 Wiley-Liss，Inc.

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