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首页> 外文期刊>Journal of magnetic resonance imaging: JMRI >Submillimeter isotropic resolution carotid wall MRI with swallowing compensation: imaging results and semiautomated wall morphometry.
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Submillimeter isotropic resolution carotid wall MRI with swallowing compensation: imaging results and semiautomated wall morphometry.

机译：具有吞咽补偿功能的亚毫米各向同性分辨率颈动脉壁MRI：成像结果和半自动壁形态测量。

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PURPOSE: To assess a swallowing-compensated, three-dimensional (3D) diffusion-prepared segmented steady-state free precession (3D Nav-D-SSFP) technique for carotid wall MRI with 0.6-mm isotropic spatial resolution, and its utility for semiautomated carotid wall morphometry. MATERIALS AND METHODS: The carotid arteries of seven healthy volunteers (N=14) were imaged with 3D Nav-D-SSFP and black-blood T2-weighted (T2w) two-dimensional (2D) fast spin-echo (FSE). Carotid wall-lumen contrast-to-noise ratio (CNR) was measured with both sequences. Measurement of carotid wall area (WA) and lumen area (LA) made in a semiautomated manner off of the 3D Nav-D-SSFP images were compared to those made manually. RESULTS: Adjusted for voxel volume and number of slices, a near six-fold improvement in CNR per unit time was achieved with 3D Nav-D-SSFP relative to 2D T2w FSE (P<0.001). Manual and semiautomated measurements of carotid WA and LA on the 3D Nav-D-SSFP images were highly correlated (intraclass correlation coefficient (ICC)=0.961 and 0.996, respectively; P<0.001). CONCLUSION: 3D Nav-D-SSFP is a time-efficient, swallowing-compensated, black-blood technique that lends itself for semiautomated measurements of carotid WA and LA that are in good agreement with manual measurements.
机译：目的：评估吞咽补偿，三维（3D）扩散准备的分段稳态自由进动（3D Nav-D-SSFP）技术用于0.6毫米各向同性空间分辨率的颈动脉壁MRI及其在半自动中的实用性颈动脉壁形态。材料与方法：用3D Nav-D-SSFP和黑血T2加权（T2w）二维（2D）快速自旋回波（FSE）对7名健康志愿者（N = 14）的颈动脉成像。用这两个序列测量颈动脉腔内腔对比度噪声比（CNR）。将3D Nav-D-SSFP图像以半自动方式进行的颈动脉壁面积（WA）和管腔面积（LA）的测量与手动进行的测量进行比较。结果：调整了体素的体积和切片的数量，使用3D Nav-D-SSFP相对于2D T2w FSE，每单位时间的CNR改善了近6倍（P <0.001）。手动和半自动测量3D Nav-D-SSFP图像上的颈动脉WA和LA高度相关（类内相关系数（ICC）分别为0.961和0.996; P <0.001）。结论：3D Nav-D-SSFP是一种省时，可吞咽补偿的黑血技术，适用于颈动脉WA和LA的半自动测量，与手动测量非常吻合。

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