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首页> 外文期刊>The Tohoku Journal of Experimental Medicine >The impact of high-density barium use in double contrast radiographic methods for gastric cancer screening in niigata, Japan.
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The impact of high-density barium use in double contrast radiographic methods for gastric cancer screening in niigata, Japan.

机译：高密度钡的使用对日本新泻地区胃癌筛查的双对比射线照相方法的影响。

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摘要

Use of high-density barium (= or > 180 w/v%) has been widely spread in community-based mass screening for gastric cancer in Japan. However, the impact on outcomes of the screening has not been fully evaluated. Then, we investigated the advantage of high-density barium use by comparing the outcomes between a period with high-density barium and that with low-density barium (< 180 w/v%) each for 3 consecutive years between 1991and 2002 at 5 medical examination organizations in Niigata Prefecture, Japan. Multivariate logistic regression analysis adjusted for age, sex and medical organization revealed that the introduction of high-density barium decreases the positive finding rate in initial mass screening x-ray examinations by 12% (odds ratio, 0.88; 95% confidence interval, 0.86 - 0.90) and increase the gastric cancer detection rate by diagnostic examination by 15% (odds ratio, 1.15; 95% confidence interval, 1.01-1.31). We conclude that introduction of high-density barium has improved the efficiency of mass screening for gastric cancer by decreasing unnecessary diagnostic examinations and reducing the total personal and public health costs. Thus, nationwide use of high-density barium is recommended for mass gastric cancer screening in Japan.
机译：在日本，基于密度的钡（=或> 180 w / v％）的使用已在基于社区的胃癌大规模筛查中广泛传播。但是，尚未完全评估对筛查结果的影响。然后，我们通过比较1991年至2002年之间连续5年高密度钡和低密度钡（<180 w / v％）的时期在5个医疗条件下的使用结果，研究了高密度钡的使用优势日本新泻县的考试机构。根据年龄，性别和医疗机构进行的多因素logistic回归分析显示，高密度钡的引入使初始质量筛查X射线检查的阳性发现率降低了12％（优势比，0.88; 95％置信区间，0.86- 0.90），并通过诊断检查将胃癌的检出率提高15％（赔率，1.15; 95％置信区间，1.01-1.31）。我们的结论是，通过减少不必要的诊断检查并减少个人和公共卫生总费用，高密度钡的引入提高了胃癌大规模筛查的效率。因此，在日本，建议在全国范围内使用高密度钡进行大规模胃癌筛查。

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