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首页> 外文期刊>Journal of medicinal food >Loss of body weight and fat and improved lipid profiles in obese rats fed apple pomace or apple juice concentrate
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Loss of body weight and fat and improved lipid profiles in obese rats fed apple pomace or apple juice concentrate

机译：饲喂苹果渣或浓缩苹果汁的肥胖大鼠的体重和脂肪减少和脂质状况改善

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摘要

The purpose of this study was to investigate the influence of apple pomace (AP) and apple juice concentrate (AC) supplementation on body weight and fat loss as well as lipid metabolism in obese rats fed a high-fat diet. Diet-induced obese rats were assigned to three groups (n=8 for each group): high fat diet (HFD) control, HFD containing 10% (w/w) AP, and HFD containing 10% (w/w) AC. There was also a normal diet group (n=8). After 5 weeks, body weight gain, adipose tissue weight, serum and hepatic lipid profiles, liver morphology, and adipocyte size were measured. Body weight gain, white adipose tissue (WAT) weight, serum total cholesterol, low-density lipoprotein cholesterol and triglyceride concentrations, epididymal adipocyte size, and lesion scores were significantly lower and serum high-density lipoprotein cholesterol concentration and brown adipose tissue weights were significantly higher in the AP and AC groups compared with the HFD group. In addition, atherogenic indices in the AP and AC groups were significantly lower than in the HFD group. These results indicate that supplementing apple products such as AP and AC may help suppress body weight and WAT gain, as well as improve lipid profiles in diet-induced obese rats.
机译：这项研究的目的是调查苹果果渣（AP）和苹果汁浓缩物（AC）补充对高脂饮食肥胖大鼠体重和脂肪损失以及脂质代谢的影响。饮食诱导的肥胖大鼠分为三组（每组n = 8）：高脂饮食（HFD）对照，HFD含10％（w / w）AP和HFD含10％（w / w）AC。还有一个正常的饮食组（n = 8）。 5周后，测量体重增加，脂肪组织重量，血清和肝脂质谱，肝形态和脂肪细胞大小。体重增加，白色脂肪组织（WAT）重量，血清总胆固醇，低密度脂蛋白胆固醇和甘油三酸酯浓度，附睾脂肪细胞大小和病变评分显着降低，血清高密度脂蛋白胆固醇浓度和棕色脂肪组织重量显着降低AP组和AC组比HFD组更高。此外，AP组和AC组的动脉粥样硬化指数均显着低于HFD组。这些结果表明，补充苹果产品（如AP和AC）可能有助于抑制体重和增加WAT，并改善饮食诱发的肥胖大鼠的脂质分布。

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