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首页> 外文期刊>Journal of medicinal food >Banana resistant starch and its effects on constipation model mice
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Banana resistant starch and its effects on constipation model mice

机译：香蕉抗性淀粉及其对便秘模型小鼠的影响

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Banana resistant starch (BRS) was extracted to investigate the structural properties of BRS, its effects on the gastrointestinal transit, and dejecta of normal and experimentally constipated mice. The mouse constipation model was induced by diphenoxylate administration. The BRS administered mice were divided into three groups and gavaged with 1.0, 2.0, or 4.0 g/kg body weight BRS per day. The small intestinal movement, time of the first black dejecta, dejecta granules, weight and their moisture content, body weight, and food intake of mice were studied. Results showed that the BRS particles were oval and spindly and some light cracks and pits were in the surface. The degree of crystallinity of BRS was 23.13%; the main diffraction peaks were at 2θ 15.14, 17.38, 20.08, and 22.51. The degree of polymerization of BRS was 81.16 and the number-average molecular weight was 13147.92 Da, as determined by the reducing terminal method. In animal experiments, BRS at the dose of 4.0 g/kg body weight per day was able to increase the gastrointestinal propulsive rate, and BRS at the doses of 2.0 and 4.0 g/kg body weight per day was found to shorten the start time of defecation by observing the first black dejecta exhaust. However, there were no influences of BRS on the dejecta moisture content, the dejecta granules and their weight, body weight, or daily food intake in mice. BRS was effective in accelerating the movement of the small intestine and in shortening the start time of defecation, but did not impact body weight and food intake. Therefore, BRS had the potential to be useful for improving intestinal motility during constipation.
机译：提取香蕉抗性淀粉（BRS）来研究BRS的结构特性，其对正常和实验性便秘小鼠胃肠道运输和沮丧的影响。小鼠便秘模型是通过苯乙氧基化物给药诱导的。施用BRS的小鼠分为三组，每天喂食1.0、2.0或4.0 g / kg体重的BRS。研究小鼠的小肠运动，第一次黑色粪便的时间，粪便颗粒，体重及其水分，体重和食物摄入。结果显示，BRS颗粒呈椭圆形且呈刺状，表面有一些轻度的裂纹和凹坑。 BRS的结晶度为23.13％。主要衍射峰位于2θ15.14、17.38、20.08和22.51。通过还原末端法测定，BRS的聚合度为81.16，数均分子量为13147.92Da。在动物实验中，每天4.0 g / kg体重的BRS能够提高胃肠道的推进速度，发现每天2.0和4.0 g / kg体重的BRS可以缩短胃肠道的启动时间。通过观察第一个黑色粪便排气来排便。但是，BRS对小鼠粪便的水分含量，粪便颗粒及其重量，体重或每日食物摄入量没有影响。 BRS在加速小肠运动和缩短排便开始时间方面是有效的，但不影响体重和食物摄入。因此，BRS具有改善便秘过程中肠蠕动的潜力。

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