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Peri-implant bone formation and surface characteristics of rough surface zirconia implants manufactured by powder injection molding technique in rabbit tibiae

机译:用粉末注射成型技术制备的兔胫骨表面粗糙的氧化锆种植体的骨周围骨形成和表面特征

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摘要

Objective: To evaluate osseointegration in rabbit tibiae and to investigate surface characteristics of novel zirconia implants made by powder injection molding (PIM) technique, using molds with and without roughened inner surfaces. Material and methods: A total of 20 rabbits received three types of external hex implants with identical geometry on the tibiae: machined titanium implants, PIM zirconia implants without mold etching, and PIM zirconia implants with mold etching. Surface characteristics of the three types of implant were evaluated. Removal torque tests and histomorphometric analyses were performed. Results: The roughness of PIM zirconia implants was higher than that of machined titanium implants. The PIM zirconia implants exhibited significantly higher bone-implant contact and removal torque values than the machined titanium implants (P < 0.001). The PIM zirconia implants using roughened mold showed significantly higher removal torque values than PIM zirconia implants without using roughened mold (P < 0.001). Conclusions: It is concluded that the osseointegration of PIM zirconia implant is promising and PIM using roughened mold etching technique can produce substantially rough surfaces on zirconia implants.
机译:目的:评估兔胫骨骨整合情况,并研究采用粉末注射成型(PIM)技术制作的新型氧化锆植入物的表面特性,该植入物使用带有和不带有粗糙内表面的模具。材料和方法:总共20只兔子在胫骨上接受了三种类型的,具有相同几何形状的外部六角形植入物:机加工的钛植入物,不带模具蚀刻的PIM氧化锆植入物和带模具蚀刻的PIM氧化锆植入物。评估了三种类型的植入物的表面特性。进行了去除扭矩测试和组织形态分析。结果:PIM氧化锆植入物的粗糙度高于机械加工的钛植入物。与机械加工的钛植入物相比,PIM氧化锆植入物显示出更高的骨-植入物接触和去除扭矩值(P <0.001)。与不使用粗糙模具的PIM氧化锆植入物相比,使用粗糙模具的PIM氧化锆植入物显示出更高的去除扭矩值(P <0.001)。结论:结论是PIM氧化锆植入物的骨整合是有前途的,并且使用粗糙模具蚀刻技术的PIM可以在氧化锆植入物上产生基本上粗糙的表面。

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