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首页> 外文期刊>Journal of Molecular Liquids >A green approach to phytomediated synthesis of silver nanoparticles using Sambucus nigra L. fruits extract and their antioxidant activity
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A green approach to phytomediated synthesis of silver nanoparticles using Sambucus nigra L. fruits extract and their antioxidant activity

机译：用黑色接骨木果实提取物进行植物介导的银纳米粒子的光化学合成的绿色方法及其抗氧化活性

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摘要

A simple and eco-friendly method for the phytomediated synthesis of silver nanoparticles (AgNPs) using European black elderberry (Sambucus nigra) fruit extracts was developed. The obtained AgNPs were characterized. The UV-Vis absorption spectrum of the biologically reduced silver showed a surface plasmon peak at 407 nm, characteristic for silver colloidal solutions. The average size of the biosynthesized, spherical in shape, nanoparticles was 26 nm, as revealed by transmission electron microscopy (TEM) analysis. The crystalline structure of metallic silver was confirmed by X-ray diffraction (XRD) analysis. The antioxidant properties of the obtained biomaterial were assessed in vitro, using the 2,2'-azinobis-3-ethyl-benzthiazino-6-sulphonic acid (ABTS) radical cation decolorization test. The in vivo antioxidant activity of the AgNPs was investigated against carrageenan-induced oxidative stress in Wistar rats. The results suggest that Black elderberry fruit extract mediated synthesized AgNPs present promising antioxidant activity and hence have a great potential in the development of therapeutic agents against oxidative tissue injuries. (C) 2016 Elsevier B.V. All rights reserved.
机译：开发了一种使用欧洲黑接骨木（Sambucus nigra）果实提取物进行植物介导的银纳米颗粒（AgNPs）植物介导合成的简单环保方法。对获得的AgNP进行表征。生物还原的银的UV-Vis吸收光谱在407 nm处显示表面等离激元峰，这是银胶体溶液的特征。如透射电子显微镜（TEM）分析所揭示，生物合成的球形球形纳米颗粒的平均尺寸为26nm。金属银的晶体结构通过X射线衍射（XRD）分析确认。使用2,2'-叠氮基双-3-乙基-苯并噻嗪基-6-磺酸（ABTS）自由基阳离子脱色测试，对获得的生物材料的抗氧化性能进行了体外评估。研究了AgNPs的体内抗氧化活性对角叉菜胶诱导的Wistar大鼠的氧化应激的影响。结果表明，黑接骨木浆果果实提取物介导的合成AgNPs具有良好的抗氧化活性，因此在开发抗氧化组织损伤的治疗剂方面具有巨大潜力。 （C）2016 Elsevier B.V.保留所有权利。

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