...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of nanomaterials >Restoration of Critical-Sized Defects in the Rabbit Mandible Using Autologous Bone Marrow Stromal Cells Hybridized with Nano-β-tricalcium Phosphate/Collagen Scaffolds
【24h】

Restoration of Critical-Sized Defects in the Rabbit Mandible Using Autologous Bone Marrow Stromal Cells Hybridized with Nano-β-tricalcium Phosphate/Collagen Scaffolds

机译：使用纳米β-磷酸三钙/胶原支架杂交的自体骨髓基质细胞修复兔下颌骨关键性缺损

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Nano-β-tricalcium phosphate/collagen (n-β-TCP/Col) is considered with good osteoconductivity. However, the therapeutic effectiveness of n-β-TCP/Col scaffolds in combination with autologous bone marrow stromal cells (BMSCs) remains to be elucidated for the repair of critical-sized bone defects. In this study, we found that n-β-TCP/Col scaffolds exhibited high biocompatibility in vitro. The introduction of BMSCs expanded in vitro to the scaffolds dramatically enhanced their efficiency to restore critical-sized bone defects, especially during the initial stage after implantation. Collectively, these results suggest that autologous BMSCs in n-β-TCP/Col scaffolds have the potential to be applied in bone tissue engineering.
机译：纳米-β-磷酸三钙/胶原蛋白（n-β-TCP/ Col）被认为具有良好的骨传导性。然而，n-β-TCP/ Col支架与自体骨髓基质细胞（BMSCs）结合的治疗效果尚待阐明，以修复关键尺寸的骨缺损。在这项研究中，我们发现n-β-TCP/ Col支架在体外具有很高的生物相容性。 BMSCs在体外扩展到支架的引入极大地提高了它们修复临界大小的骨缺损的效率，尤其是在植入后的初期。总体而言，这些结果表明，n-β-TCP/ Col支架中的自体BMSC具有在骨组织工程中应用的潜力。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号