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首页> 外文期刊>Clinical oral implants research >Effect of anorganic bovine bone to autogenous cortical bone ratio upon bone remodeling patterns following maxillary sinus augmentation.
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Effect of anorganic bovine bone to autogenous cortical bone ratio upon bone remodeling patterns following maxillary sinus augmentation.

机译：上颌窦增大后，无机牛骨与自体皮质骨比例对骨重塑模式的影响。

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INTRODUCTION: Maxillary sinus augmentation is a predictable implant site development technique, although several local and systemic factors may influence outcomes. The aim of this study was to evaluate healing patterns and bone remodeling activity following the use of two different graft mixtures for maxillary sinus augmentation. MATERIALS AND METHODS: Patients in need of maxillary sinus augmentation were randomly assigned to two different groups. A graft mixture using a 50% autologous bone (AB) to 50% anorganic bovine bone (ABB) ratio was used in group 1, while a 20% AB to 80% ABB ratio was utilized for group 2. After a 6-month healing period, bone core biopsies were harvested for histological, histomorphometrical, and immunohistochemical analyses. RESULTS: Twenty-eight subjects participated in this study. No statistically significant differences were found between groups in regards to vital bone and non-mineralized tissue proportions. Higher number of osteoid lines (18.05 +/- 10.06 in group 1 vs. 9.01 +/- 7.53 in group 2; P = 0.023) and higher cellularity, particularly regarding the number of osteocytes (631.85 +/- 607.98 in group 1 vs. 219.08 +/- 103.26 in group 2; P = 0.002), were observed in specimens from group 1. Differences in expression patterns of osteopontin and tartrate-resistant acid phosphatase were also detected between groups. CONCLUSION: AB to ABB ratio appears to influence bone remodeling patterns and cell content following maxillary sinus augmentation procedures. Similar proportion of vital bone was found in specimens obtained from both groups. More cellular presence was observed in samples containing higher proportions of AB.
机译：简介：上颌窦增大术是一种可预测的植入部位发展技术，尽管一些局部和全身性因素可能会影响预后。这项研究的目的是评估在使用两种不同的移植混合物进行上颌窦增大后的愈合模式和骨重塑活性。材料与方法：将需要上颌窦增大术的患者随机分为两组。第1组使用了50％自体骨（AB）与50％无机牛骨（ABB）比例的移植物混合物，而第2组使用了20％AB与80％ABB的比例的移植物。在此期间，收集骨芯活检组织用于组织学，组织形态计量学和免疫组织化学分析。结果：28名受试者参加了这项研究。两组之间在重要骨骼和非矿化组织比例方面没有发现统计学上的显着差异。骨样细胞系数目更高（第1组为18.05 +/- 10.06，第2组为9.01 +/- 7.53; P = 0.023）和更高的细胞流动性，尤其是关于骨细胞的数量（第1组为631.85 +/- 607.98对。在第1组的标本中观察到第2组为219.08 +/- 103.26; P = 0.002），在各组之间也检测到骨桥蛋白和抗酒石酸酸性磷酸酶的表达模式差异。结论：上颌窦增大手术后，AB与ABB的比例似乎会影响骨重塑模式和细胞含量。从两组获得的标本中，活骨的比例相似。在含有更高比例的AB的样品中观察到更多的细胞存在。

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