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首页> 外文期刊>Journal of Non-Crystalline Solids: A Journal Devoted to Oxide, Halide, Chalcogenide and Metallic Glasses, Amorphous Semiconductors, Non-Crystalline Films, Glass-Ceramics and Glassy Composites >Biodegradation behavior of chitosan/calcium phosphate composites
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Biodegradation behavior of chitosan/calcium phosphate composites

机译：壳聚糖/磷酸钙复合材料的生物降解行为

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A variety of biomimetic materials with structural and mechanical equivalence to bone have been developed to repair bone defects. Chitosan/calcium phosphate composites composed of bioactive calcium phosphate and flexible chitosan were made by a simple mixing-and-heating method. Mechanical properties, morphology, phase composition, and weight change after immersion in Hanks' solution were evaluated. Experimental results showed that the formation of pores/cracks on immersed sample surface obviously depended on the calcium phosphate content and immersion time. The immersion time imposed in this study did have a statistically significant effect on mechanical properties. When immersed for 90 days in Hanks' solution, the strength of immersed composites containing 10 wt/v% calcium phosphate with the initial strength of 27 MPa was about 2 MPa, having a reduction of 92%. Based on the above results, the organic-inorganic hybrid composites with high initial strength might be an acceptable material candidate for bone tissue repair. (C) 2007 Elsevier B.V. All rights reserved.
机译：已经开发了与骨骼具有结构和机械等效性的多种仿生材料来修复骨骼缺陷。由生物活性磷酸钙和柔性壳聚糖组成的壳聚糖/磷酸钙复合材料是通过简单的混合加热方法制成的。评估了浸入汉克斯溶液后的力学性能，形态，相组成和重量变化。实验结果表明，浸没样品表面孔/裂纹的形成明显取决于磷酸钙含量和浸没时间。在这项研究中施加的浸泡时间确实对机械性能具有统计学上的显着影响。当在汉克斯溶液中浸泡90天时，初始强度为27 MPa的含10 wt / v％磷酸钙的复合材料的浸泡强度约为2 MPa，降低了92％。基于以上结果，具有高初始强度的有机-无机杂化复合材料可能是可接受的骨组织修复材料。 （C）2007 Elsevier B.V.保留所有权利。

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