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首页> 外文期刊>Journal of neuro-ophthalmology: Official journal of the North American Neuro-Ophthalmology Society >Sato DK, Callegaro D, Lana-Peixoto MA, Waters PJ, Jorge FM, Takahashi T, Nakashima I, Apostolos-Pereira SL, Talim N, Simm RF, Lino AM, Misu T, Leite MI, Aoki M, Fujihara K. Distinction between MOG antibody-positive and AQP4 antibodypositive NMO spectrum disorders. Neurology. 2014;82:474-481.
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Sato DK, Callegaro D, Lana-Peixoto MA, Waters PJ, Jorge FM, Takahashi T, Nakashima I, Apostolos-Pereira SL, Talim N, Simm RF, Lino AM, Misu T, Leite MI, Aoki M, Fujihara K. Distinction between MOG antibody-positive and AQP4 antibodypositive NMO spectrum disorders. Neurology. 2014;82:474-481.

机译：Sato DK，Callegaro D，Lana-Peixoto MA，Waters PJ，Jorge FM，Takahashi T，Nakashima I，Apostolos-Pereira SL，Talim N，Simm RF，Lino AM，Misu T，Leite MI，Aoki M，Fujihara K.在MOG抗体阳性和AQP4抗体阳性NMO谱障碍之间。神经病学。 2014; 82：474-481。

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In this retrospective study, the authors searched their databases for patients with a history of optic neuropathy who underwent macular optical coherence tomography testing. They found that 16 of 180 eyes had microcystic macular edema (MME) limited to the inner nuclear layer. A striking finding was the perifoveal location of the MME in all eyes. The cause of the optic neuropathy ranged from compressive (n = 9), vascular (n = 3), hereditary (n = 2), and idiopathic (n = 2), and the proportions did not differ from the non-MME eyes. The shortest time to develop MME was 4 months and the longest time was several years. The authors make a compelling argument that this represents a retrograde degenerative process. I actually have seen these changes on optical coherence tomography in patients with optic neuropathy, but did not associate the findings. I had assumed that the patient had developed cystic retinal changes and made a referral to a retinal specialist. Now I know. It has a pretty characteristic appearance, and I would recommend the reader look at the images.
机译：在这项回顾性研究中，作者在他们的数据库中搜索了经历过黄斑光学相干断层扫描测试的视神经病变病史的患者。他们发现180只眼中有16只眼的微囊性黄斑水肿（MME）局限于核内层。一个令人惊讶的发现是在所有眼睛中MME的中央凹位置。视神经病变的原因包括压迫性（n = 9），血管性（n = 3），遗传性（n = 2）和特发性（n = 2），其比例与非MME眼睛相同。开发MME的最短时间是4个月，最长的时间是几年。作者提出了令人信服的论点，认为这代表了逆行的退化过程。我实际上已经在视神经病患者的光学相干断层扫描中看到了这些变化，但没有发现相关的结果。我以为该患者出现了视网膜囊性变，并转诊给视网膜专家。现在我知道。它具有漂亮的外观，我建议读者看一下图像。

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