Complement activation and CD59 expression in the motor facial nucleus following intracranial transection of the facial nerve in the adult rat.

Mattsson P; Morgan BP; Svensson M

首页> 外文期刊>Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology >Complement activation and CD59 expression in the motor facial nucleus following intracranial transection of the facial nerve in the adult rat.

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Complement activation and CD59 expression in the motor facial nucleus following intracranial transection of the facial nerve in the adult rat.

机译：成年大鼠颅内横断面神经后，运动面神经核中的补体激活和CD59表达。

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Intracranial transection of the facial nerve has been shown to cause a massive neuronal cell death in the motor facial nucleus. Complement activation has been proposed to contribute to neuronal degeneration following axotomy. Using immunocytochemistry and in situ hybridization we show in the present study that there is complement activation in the facial nucleus after intracranial facial nerve transection as well as increase of the complement regulators CD59 and clusterin. We propose a neuroprotective role for the complement regulators CD59 and clusterin against homologous attack of complement to facial motor neurons.

机译：面神经的颅内横断显示已导致运动性面核大量神经元细胞死亡。已经提出补体激活有助于轴切术后神经元变性。使用免疫细胞化学和原位杂交，我们在本研究中显示颅内面部神经横断后，面部核中的补体激活以及补体调节剂CD59和clusterin的增加。我们提出补体调节剂CD59和簇蛋白对补体对面部运动神经元的同源攻击的神经保护作用。

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《Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology》 |1998年第2期|共10页
作者
Mattsson P; Morgan BP; Svensson M;
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正文语种 eng
中图分类神经病学与精神病学;医学免疫学;
关键词
Antigens; CD59; Complement Activation; Facial Nerve; Motor Neurons; clusterin; 抗原; CD59; 补体激活; 面神经; 运动神经元;

机译：Antigens;CD59;Complement Activation;Facial Nerve;Motor Neurons;clusterin;抗原;CD59;补体激活;面神经;运动神经元;

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1. Complement activation and CD59 expression in the motor facial nucleus following intracranial transection of the facial nerve in the adult rat. [J] . Mattsson P, Morgan BP, Svensson M Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology . 1998,第1a2期

机译：成年大鼠颅内横断面神经后，运动面神经核中的补体激活和CD59表达。
2. Motor neuronal and glial apoptosis in the adult facial nucleus after intracranial nerve transection. [J] . Mattsson P, Delfani K, Janson AM, Journal of neurosurgery. . 2006,第3期

机译：颅内神经横断后成人面核的运动神经元和胶质细胞凋亡。
3. The novel pyrrolopyrimidine PNU-101033-E improves facial motor neuron survival following intracranial axotomy of the facial nerve in the adult rat. [J] . Mattsson P, Aldskogius H, Svensson M Journal of neurotrauma . 1999,第9期

机译：新型吡咯并嘧啶PNU-101033-E改善了成年大鼠颅内轴突切开术后面部运动神经元的存活。
4. Computerized diagnosis of facial nerve palsy based on optical flow analysis of facial expressions [C] . Minamitani, H., Hoshino, Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE . 2003

机译：基于面部表情光流分析的面神经麻痹的计算机诊断
5. Asymmetry in forensic 3-D facial reconstruction: An assessment of facial asymmetry in adult First Nations Nova Scotian facial soft tissue depth data [D] . MacNeil, John Alexander Barra 2011

机译：法医3-D面部重建中的不对称性：成人原住民新斯科舍省面部软组织深度数据中面部不对称性的评估
6. Effects of facial nerve axotomy on Th2- and Th1-associated chemokine expression in the facial motor nucleus of wild-type and pre-symptomatic mSOD1 mice [O] . Derek A. Wainwright, Junping Xin, Nichole A. Mesnard, -1

机译：面神经轴突对野生型和前症状MSOD1小鼠面部电机核的Th2-和Th1相关趋化因子表达的影响
7. Long-term adeno-associated viral vector-mediated expression of truncated TrkB in the adult rat facial nucleus results in motor neuron degeneration [O] . de Wit, Joris, Eggers, R, Evers, R, 2006

机译：腺相关病毒载体介导的成年大鼠面核中TrkB的长期表达导致运动神经元变性

Complement activation and CD59 expression in the motor facial nucleus following intracranial transection of the facial nerve in the adult rat.

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