首页> 外文期刊>Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology >An early and sustained peripheral inflammatory response in acute ischaemic stroke: relationships with infection and atherosclerosis.
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An early and sustained peripheral inflammatory response in acute ischaemic stroke: relationships with infection and atherosclerosis.

机译:急性缺血性中风的早期和持续性外周炎症反应:与感染和动脉粥样硬化的关系。

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摘要

Central nervous system and peripheral inflammation is important in the responses to ischaemic stroke, and may also predispose to its development. We aimed to identify (1) the extent to which a peripheral inflammatory response is activated in patients following acute stroke, and (2) whether there was evidence for preexisting peripheral inflammation. Thirty-six patients with ischaemic stroke within 12 h of onset of symptoms had serial blood samples taken up to 12 months for analysis of markers of inflammation. Thirty-six control subjects, individually matched for age, sex and degree of atherosclerosis, were also studied. Median C-reactive protein (CRP) was elevated, relative to controls (2.08 mg/l), from admission (4.31 mg/l) (p
机译:中枢神经系统和周围炎症在对缺血性中风的反应中很重要,并且也可能促进其发展。我们的目的是确定(1)急性中风后患者外周炎症反应的激活程度,以及(2)是否存在先前存在外周炎症的证据。在症状发作后12小时内的36例缺血性中风患者需要采集长达12个月的血样以分析炎症标志物。还对年龄,性别和动脉粥样硬化程度分别匹配的36名对照受试者进行了研究。从入院(4.31 mg / l)(p

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