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Do drugs of abuse impact on HIV disease?

机译:滥用药物会影响HIV疾病吗?

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摘要

Drug abuse, certain lifestyles, access and adherence to drug abuse treatment, and medical consequences of drug abuse remain as important factors that impact on HIV disease among AIDS patients worldwide. Most in vitro and in vivo studies show a significant impact on HIV disease. Epidemiological studies in the past have failed to support these observations. However, new and limited evidence shows that drug abuse may accelerate HIV disease in humans. Research is needed to design new or refine known techniques that more closely mimic natural conditions of HIV disease, and perform additional assessments of basic laboratory, clinical, and epidemiological data to determine whether drug abuse significantly impacts on HIV disease.
机译:药物滥用,某些生活方式,对药物滥用治疗的获得和坚持以及药物滥用的医疗后果仍然是影响全世界AIDS患者中HIV疾病的重要因素。大多数体外和体内研究表明对HIV疾病有重大影响。过去的流行病学研究未能支持这些观察结果。但是,新的有限证据表明,药物滥用可能会加速人类的艾滋病毒感染。需要进行研究以设计新的或改进的已知技术,以更紧密地模仿HIV疾病的自然状况,并对基础实验室,临床和流行病学数据进行额外评估,以确定吸毒是否对HIV疾病有重大影响。

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