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首页> 外文期刊>Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology >Expression pattern of activation and adhesion molecules on peripheral blood CD4+ T-lymphocytes in relapsing-remitting multiple sclerosis patients: a serial analysis.
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Expression pattern of activation and adhesion molecules on peripheral blood CD4+ T-lymphocytes in relapsing-remitting multiple sclerosis patients: a serial analysis.

机译：复发性多发性硬化症患者外周血CD4 + T淋巴细胞上活化和粘附分子的表达模式：系列分析。

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摘要

We studied the expression of various cell surface molecules (CD25, CD28, CD29, CD45RO, CD56, LFA-1, VLA-4) on peripheral blood CD4+ T-cells in 6 relapsing-remitting multiple sclerosis (RR-MS) patients. Furthermore, changes in the expression pattern of these surface markers during intervals of increased disease activity, which was measured by gadolinium (Gd-DTPA) magnetic resonance imaging (MRI) were examined. Although several patients showed signs of increased disease activity during the observation period, this was not paralleled by a relevant change in the expression of these activation and adhesion molecules.
机译：我们研究了6名复发缓解型多发性硬化症（RR-MS）患者外周血CD4 + T细胞上各种细胞表面分子（CD25，CD28，CD29，CD45RO，CD56，LFA-1，VLA-4）的表达。此外，检查了在疾病活动性增加期间，这些表面标志物表达模式的变化，该变化通过changes（Gd-DTPA）磁共振成像（MRI）测量。尽管在观察期间有几例患者表现出疾病活动增加的迹象，但这些活化和粘附分子表达的相关变化却没有与此相提并论。

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