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首页> 外文期刊>Journal of natural products >New jaspamide derivatives from the marine sponge Jaspis splendans collected in Vanuatu.
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New jaspamide derivatives from the marine sponge Jaspis splendans collected in Vanuatu.

机译:来自瓦努阿图的海洋海绵锦葵中的新jasbamide衍生物。

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摘要

Two new jaspamide derivatives (1 and 2) along with jaspamide have been isolated from the marine sponge Jaspis splendans collected in Vanuatu. Their chemical structures were determined from 1D and 2D NMR studies and MS data. These two compounds inhibited the in vitro growth of the NSCLC-N6 human tumor cell lines with IC50 values in the microg/mL range.
机译:从瓦努阿图收集的海生海绵Jaspis splendans中分离了两种新的jaspamide衍生物(1和2)以及jaspamide。它们的化学结构由1D和2D NMR研究以及MS数据确定。这两种化合物抑制了NSCLC-N6人肿瘤细胞系的体外生长,IC50值在microg / mL范围内。

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