Erinacine S, a Rare Sesterterpene from the Mycelia of Hericium erinaceus

Chen Chien-Chih; Tzeng Tsai-Teng; Chen Chin-Chu; Ni Ching-Li; Lee Li-Ya; Chen Wan-Ping; Shiao Young-Ji; Shen Chien-Chang

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Erinacine S, a Rare Sesterterpene from the Mycelia of Hericium erinaceus

机译：Erinacine S，一种来自猴头菌属菌丝体的稀有的倍甾烯

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A new sesterterpene, erinacine S, and one cyathane diterpene xyloside, erinacine A, were isolated from the ethanol extract of the mycelia of Hericium erinaceus. Their structures were elucidated by spectroscopic and X-ray analysis. A 30-day oral course of erinacines A and S attenuated A beta plaque burden in the brains of 5-month-old female APP/PS1 transgenic mice. Moreover, erinacines A and S significantly increased the level of insulin-degrading enzyme in cerebral cortex.

机译：从猴头菌的菌丝体的乙醇提取物中分离出一种新的酯基萜烯，erinacine S和一种胞苷二萜木糖苷，erinacineA。通过光谱和X射线分析阐明了它们的结构。在30个月的口服过程中，erinacines A和S减轻了5个月大的APP / PS1转基因雌性小鼠大脑中Aβ斑块的负担。此外，erinacines A和S显着增加了大脑皮层中胰岛素降解酶的水平。

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《Journal of natural products》 |2016年第2期|共4页
作者
Chen Chien-Chih; Tzeng Tsai-Teng; Chen Chin-Chu; Ni Ching-Li; Lee Li-Ya; Chen Wan-Ping; Shiao Young-Ji; Shen Chien-Chang;
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中图分类生药学（天然药物学）;
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1. Erinacine S, a Rare Sesterterpene from the Mycelia of Hericium erinaceus [J] . Chen Chien-Chih, Tzeng Tsai-Teng, Chen Chin-Chu, Journal of natural products . 2016,第2期

机译：Erinacine S，一种来自猴头菌属菌丝体的稀有的倍甾烯
2. Thirteen-Week Oral Toxicity Evaluation of Erinacine A-Enriched Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), Mycelia in Sprague-Dawley Rats [J] . Lee Li-Ya, Li I-Chen, Chen Wan-Ping, International Journal of Medicinal Mushrooms . 2019,第4期

机译：13周的口腔毒性评估ErinaCine A-Emiched Lion的鬃毛药用蘑菇，猴子erinaceus（姬松茸），在Sprague-Dawley大鼠菌丝体
3. Neurohealth Properties of Hericium erinaceus Mycelia Enriched with Erinacines [J] . I-Chen Li, Li-Ya Lee, Tsai-Teng Tzeng, Behavioural neurology . 2018,第1期

机译：富含猴头素的猴头菇菌丝体的神经健康特性
4. Optimization of Extraction key Process for Erinacine from Hericium erinaceus [C] . Jinzhe He, Qiang Shen International Conference on Logistics, Engineering, Management and Computer Science . 2015

机译：从赫内米氏素伊尼坎的提取键过程优化
5. Proteomic Analysis of Fetal Rat Neural Stem Cells After Treatment with Hericium erinaceus [D] . Test, Bright A. 2020

机译：哌啶素治疗后胎儿大鼠神经干细胞的蛋白质组学分析
6. Preclinical Bioavailability Tissue Distribution and Protein Binding Studies of Erinacine A a Bioactive Compound from Hericium erinaceus Mycelia Using Validated LC-MS/MS Method [O] . Pei-Ching Tsai, Yi-Kai Wu, Jun-Hao Hu, 2021

机译：使用验证的LC-MS / MS法伊丽尼尼菌虫草菌菌丝体菌丝菌菌菌的生物活性化合物的临床前生物利用度组织分布和蛋白质结合研究
7. Retraction Note to: Hericium erinaceus mycelium and its isolated erinacine A protection from MPTP-induced neurotoxicity through the ER stress, triggering an apoptosis cascade [O] . Hsing-Chun Kuo, Chien-Chang Lu, Chien-Heng Shen, 2021

机译：撤回注意：哌啶菌菌丝体及其孤立的Erinacine通过ER应力保护MPTP诱导的神经毒性，引发细胞凋亡级联

Erinacine S, a Rare Sesterterpene from the Mycelia of Hericium erinaceus

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